Technical Program
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Sunday, June 23 |
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| 6:00 PM - 7:00 PM | Badge Pick-Up (Check-In) |
Monday, June 24 |
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| 7:00 AM - 12:00 PM | Registration / Check-In |
| 8:15 AM - 8:30 AM | Welcoming Remarks - Julius B. Lucks, Northwestern University and Stephanie Culler, Persephone Biome |
| 8:30 AM - 9:30 AM | Keynote Speaker: Learning About the Origin of Life from Efforts to Design an Artificial Cell Jack Szostak, Harvard University |
| 9:30 AM - 11:00 AM | Session 1 - Molecular Control, Programming and Recording Chairs: James Chappell, Rice University and Harris Wang, Columbia University |
| 9:30 AM - 10:00 AM | Invited Speaker: Biological Recording of Cellular Events on CRISPR Tape Harris Wang, Columbia University |
| 10:00 AM - 10:20 AM | Designable Modules for Protein Origami Nanostructures and Cellular Circuits Roman Jerala, National Institute of Chemistry, Slovenia |
| 10:20 AM - 10:40 AM | Transcriptional Reprogramming in Bacteria: Challenges and Opportunities with CRISPR-Cas Activators Jesse Zalatan, University of Washington |
| 10:40 AM - 11:00 AM | Engineering Redox Metabolism Using an Unnatural Cofactor Han Li, University of California, Irvine |
| 11:00 AM - 1:00 PM | Lunch/Company Engagement Company: Oriciro |
| 1:00 PM - 2:30 PM | Session 2 - The Materials Science/Synthetic Biology Interface Chair: Neha Kamat, Northwestern University |
| 1:00 PM - 1:30 PM | Invited Speaker: Engineering Microorganisms to Make and Communicate with Materials Caroline Ajo Franklin, Lawrence Berkeley National Laboratory |
| 1:30 PM - 1:50 PM | Engineered Living Materials Christopher Voigt, Massachusetts Institute of Technology |
| 1:50 PM - 2:10 PM | Communication and Quorum Sensing in Non-Living Mimics of Eukaryotic Cells Neal Krishna Devaraj, University of California, San Diego |
| 2:10 PM - 2:30 PM | Future of Material Synthesis for Military Environments Nancy Kelley-Loughnane, Air Force Research Laboratory |
| 2:30 PM - 3:00 PM | Break |
| 3:00 PM - 4:30 PM | Session 3 - Evolution for and within Synthetic Biology Chair: Jeff Barrick, University of Texas at Austin |
| 3:00 PM - 3:30 PM | Invited Speaker: Synthetic Genetic Systems for Rapid Mutation and Continuous Evolution in vivo Chang Liu, University of California, Irvine |
| 3:30 PM - 3:50 PM | Systematic Analysis of Higher-Order Genetic Interactions Using Combinatorial CRISPR-Cas9 Gene Drives Christopher W. Bakerlee, Harvard University |
| 3:50 PM - 4:10 PM | Determination of Membrane Lipid Specificity By Using in Vitro Evolution Aleksandra Šakanović, National Institute of Chemistry, Slovenia |
| 4:10 PM - 4:30 PM | Design and Application of S-Adenosylmethionine Methyltransferase Growth-Coupling for Evolutionary Engineering Anne Sofie Hansen, Technical University of Denmark |
| 4:30 PM - 5:00 PM | Break |
| 5:00 PM - 6:30 PM |
SynBio Funders Panel Aura Gimm, AFOSR |
| 6:30 PM - 7:00 PM | Rapid Fire Poster Session A Chair: Tara Deans, University of Utah |
| 7:00 PM - 8:00 PM | Poster Session A and Reception |
Tuesday, June 25 |
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| 7:00 AM - 8:00 AM | Build-A-Cell Breakfast (Pre-Registration Required) |
| 7:00 AM - 8:30 AM | Registration / Check-In |
| 8:30 AM - 9:30 AM | Keynote Speaker: Designing Biology Reshma Shetty, Ginkgo Bioworks |
| 9:30 AM - 10:00 AM | Break |
| 10:00 AM - 11:50 AM | Session 4 - Emerging Technologies and Fronteirs Chairs: James Chappell, Rice University and Nathan Hillson, LBNL |
| 10:00 AM - 10:30 AM | Invited Speaker: Talking to Cells: Biomolecular Engineering for Non-Invasive Imaging and Control of Cellular Function Mikhail Shapiro, California Institute of Technology |
| 10:30 AM - 10:50 AM | Synthetic Biology in Biomining and Microbial Corrosion Applications Scott Banta, Columbia University |
| 10:50 AM - 11:10 AM | Activating Foreign FeS Enzymes in Escherichia coli Elena Fernández-Fueyo, TU Delft |
| 11:10 AM - 11:30 AM | Mining Newly Discovered Native Plasmids for Genetic Modification of Intractable Environmental Strains and Communities Ankita Kothari, Lawrence Berkeley National Lab |
| 11:30 AM - 11:50 AM | Towards a Synthetic Metabolism: Combining Computational Pathway and Enzyme Design to Create Biosynthetic Routes to Novel Molecular Scaffolds Alexandre Zanghellini, Arzeda, Cornell University |
| 12:00 PM - 1:30 PM | Lunch/Company Engagement Company: Inscripta |
| 1:30 PM - 3:20 PM | Session 5 - Cell Free Synthetic Biology Chairs: Julius B. Lucks, Northwestern University and Harris Wang, Columbia University |
| 1:30 PM - 2:00 PM | Invited Speaker: RNA Technologies Developed Through an Internet-scale Videogame Rhiju Das, Stanford University |
| 2:00 PM - 2:20 PM | Cell-Free Gene Regulatory Network Engineering with Synthetic Transcription Factors Zoe Swank, Ecole Polytechnique Federale de Lausanne |
| 2:20 PM - 2:40 PM | Machine Learning Optimisation of Gene Construct Topology for Rapid, Cell-Free Protein Synthesis Alice M. Banks, Newcastle University, United Kingdom |
| 2:40 PM - 3:00 PM | Cell-Free Synthetic Biology in Hydrogel Chassis: Biologically Sensing and Responding Materials Colette J. Whitfield, Newcastle University, United Kingdom |
| 3:00 PM - 3:20 PM | Synthetic Cell Systems for Scalable Bio-Production of Plant Natural Products James Carothers, University of Washington |
| 3:20 PM - 4:00 PM | Break |
| 4:00 PM - 6:00 PM | Entrepreneurship Panel Chairs: Stephanie Culler, Persephone Biome, Julius B. Lucks, Northwestern University |
| 4:00 PM - 4:30 PM | Invited Speaker: John Cumbers, SynBioBeta |
| 4:30 PM - 5:10 PM | Invited Panelists Introductions, "Why/how I chose to become an entrepreneur" |
| 5:10 PM - 6:00 PM | Entrepreneurship Panel John Cumbers, SynBioBeta (Moderator) Reshma Shetty, Ginkgo Bioworks Stephanie Culler, Persephone Biome David Breslauer, Bolt Threads |
| 6:00 PM - 6:30 PM | Rapid Fire Poster Session B Chair: Jeff Barrick, University of Texas Austin |
| 6:30 PM - 7:30 PM | Poster Session B and Reception |
Wednesday, June 26 |
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| 7:30 AM - 8:30 AM | Registration / Check-In |
| 8:30 AM - 9:30 AM | Keynote Speaker: Synthetic Biology for Engineering Plant Genetic Circuits: from Predictable Electronic-like Functions to Innovative Desalination June Medford, Colorado State University |
| 9:30 AM - 10:00 AM | Break |
| 10:00 AM - 11:50 AM | Session 6 - Advances in Mammalian and Plant Synthetic Biology Chairs: Tara Deans, University of Utah and Stanley Qi, Stanford University |
| 10:00 AM - 10:30 AM | Invited Speaker: Epigenetic Engineering in Triple Negative Breast Cancer Karmella Haynes, Emory University |
| 10:30 AM - 10:50 AM | A New Platform for Synthetic Transcriptional Regulation in Human Cells Divya Israni, Boston University |
| 10:50 AM - 11:10 AM | A Tunable Dual-Input System for 'on-Demand' Regulation of Dynamic Gene Expression in Mammalian Cells Elisa Pedone, University of Bristol |
| 11:10 AM - 11:30 AM | Transcriptional Rewiring: Editing Plant Stess Response Networks Oliver Windram, Imperial College London |
| 11:30 AM - 11:50 AM | Absolute Quantification of Clock Proteins Reveals a Quantitative Engineering Path for Tuning the Arabidopsis Circadian Oscillator and Output Pathways Uriel Urquiza, The University of Edinburgh |
| 11:50 AM - 1:30 PM | Lunch/Company Engagement Companies: Twist Bioscience, m2p-labs |
| 1:30 PM - 3:30 PM | Session 7 - Sensing and Signaling within Multicellular Synthetic Biology Chairs: Mary Dunlop, Boston University and Karmella Haynes, Emory University |
| 1:30 PM - 2:00 PM | Invited Speaker: Engineering Biological Feedback Control Hana El Samad, University of California, San Francisco |
| 2:00 PM - 2:30 PM | Invited Speaker: Optogenetic Control of Gut Bacterial Metabolism Jeff Tabor, Rice University |
| 2:30 PM - 2:50 PM | Optogenetics and Regulated Phase Separation for Spatial and Temporal Control of Metabolism Jose L. Avalos, Princeton University |
| 2:50 PM - 3:10 PM | Translating an Ancient Bioelectric Language for Synthetic Biology Arthur Prindle, Northwestern University |
| 3:10 PM - 3:30 PM | Aquatic Detoxification with Tissue Engineered Multicellular Structures Nina M. Pollak, University of the Sunshine Coast, The University of Queensland, Commonwealth Scientific and Industrial Research Organisation |
| 3:30 PM - 4:00 PM | Break |
| 4:00 PM - 6:00 PM | Student/Post-Doc Session Chair: Nathan Hillson, LBNL |
| 4:00 PM - 4:15 PM | Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacteria Via Dynamic RNA Nanotechnology Mikhail Hanewich-Hollatz, California Institute of Technology |
| 4:15 PM - 4:30 PM | Toward the Evolution of an Exclusively Quadruplet-Decoding Translation System Erika DeBenedictis, Massachusetts Institute of Technology |
| 4:30 PM - 4:45 PM | Engineering Bacterial DNA Sensors Elizabeth Libby, Harvard Medical School |
| 4:45 PM - 5:00 PM | Modulating Level of the Transcription Factor Hild to Improve Titers of Secreted Heterologous Proteins By the Type III Secretion System Han Teng Wong, University of California, Berkeley |
| 5:00 PM - 5:15 PM | A Modular, Field-Deployable Cell-Free Biosensing Platform for Monitoring Water Quality Adam Silverman, Northwestern University |
| 5:15 PM - 5:30 PM | Engineering Protein-Protein Devices for Multilayered Regulation of mRNA Translation Using Orthogonal Proteases in Mammalian Cells Federica Cella, University of Genoa |
| 5:30 PM - 5:45 PM | In Vitro Transcriptional Regulatory Networks for Autonomous Control of Nucleic Acid-Responsive Materials Samuel Schaffter, Johns Hopkins University |
| 5:45 PM - 6:00 PM | Bliss: The Black List Sequence Screening Pipeline Lisa Simirenko, DOE Joint Genome Institute, Lawrence Berkeley National Laboratory |
| Free Evening | |
Thursday, June 27Conference Room: Beekman/Sutton North |
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| 7:30 AM - 8:30 AM | Registration / Check-In |
| 8:30 AM - 9:30 AM | Keynote Speaker: Engineering Genomes, Karyotypes, and the Dark Matter of the Human Genome Jef Boeke, New York University |
| 9:30 AM - 10:00 AM | Break |
| 10:00 AM - 12:15 PM | Session 8 - Emerging Applications and Frontiers Chairs: Stephanie Culler, Persephone Biome and Julius B. Lucks, Northwestern University |
| 10:00 AM - 10:30 AM | Invited Speaker: Programming Sequential Logic in Microbial Consortia and Probiotic Bacteria Lauren Andrews, University of Massachusetts Amherst |
| 10:30 AM - 10:45 AM | Massively Multiplexed Nucleic Acid Detection with Cas13 Cameron Myhrvold, Broad Institute of Harvard and MIT, Harvard University |
| 10:45 AM - 11:00 AM | Rapid, Low-Cost Detection of Water Contaminants Using Regulated in Vitro Transcriptions Khalid K. Alam, Northwestern University |
| 11:00 AM - 11:15 AM | Genetically Encoded Biosensors for Detection of Complex Human Milk Oligosaccharides Fatima Enam, Iowa State University |
| 11:15 AM - 11:30 AM | Biosynthetic Engineering and Diversification of Antibiotics in S. Cerevisiae Hala Iqbal, NYU Langone |
| 11:30 AM - 11:45 AM | Reporter Genes for Optical Coherence Tomography George J. Lu, California Institute of Technology |
| 11:45 AM - 12:00 PM | Engineering Biology: A Research Roadmap for a Next-Generation Bioeconomy Douglas Friedman, Engineering Biology Research Consortium |
| 12:00 PM - 12:15 PM | Closing Remarks: Julius Lucks, Northwestern University and Stephanie Culler, Persephone Biome |
| 12:15 PM - 1:45 PM | Lunch on your own |
| 1:45 PM - 3:45 PM | Software for Synthetic Biology Workflows Workshop |
