| 1:00 PM |
6:00 PM |
Registration |
| 3:00 PM |
3:10 PM |
Introductory remarks |
| 3:10 PM |
4:10 PM |
Keynote Speaker: Progress Toward an HIV Vaccine - Dennis Burton |
| 4:10 PM |
6:00 PM |
Session 1: Biophysical and Microscale Analyses of Molecular and Cellular Function |
| 4:10 PM |
4:35 PM |
Invited Speaker: Weighing Single Cells – Biological Insights and Clinical Opportunities - Scott Manalis |
| 4:35 PM |
4:50 PM |
Molecular-Level Characterization of the Anti-Influenza Serological Antibody Repertoire: Implications for Vaccine Development - Jiwon Lee |
| 4:50 PM |
5:05 PM |
Computational Design, Simulations and Energy Calculations in the Study of β-Wrapin Proteins in Complex with Amyloidogenic Proteins - Phanourios Tamamis |
| 5:05 PM |
5:20 PM |
Direct Observation of TALE Protein Dynamics on DNA - Charles Schroeder |
| 5:20 PM |
5:35 PM |
Advancing Cancer Immunotherapy One Cell at a Time - Navin Varadarajan |
| 5:35 PM |
6:00 PM |
Invited Speaker: Biomolecular Engineering for Noninvasive Imaging and Control of Cellular Function - Mikhail G. Shapiro |
| 6:00 PM |
7:00 PM |
Welcome Reception |
| 7:00 AM |
12:00 PM |
Registration |
| 7:45 AM |
8:15 AM |
Breakfast |
| 8:15 AM |
10:10 AM |
Session 2: Biomolecular Engineering Applications: Therapeutics, Diagnostics and Imaging Agents |
| 8:15 AM |
8:40 AM |
Invited Speaker: Supramolecular Materials for Immunotherapy - Joel H. Collier |
| 8:40 AM |
8:55 AM |
Developing a Modular Virus-like Particle Vaccine Platform for Viral Diseases - Julie Fogarty |
| 8:55 AM |
9:10 AM |
Translatable Affibody Ligand Discovery: Engineered Biopanning, Deep Sequence-Guided Library Design, and Pharmacokinetic Modulation - Benjamin J. Hackel |
| 9:10 AM |
9:25 AM |
Bioorthogonal Chemistry for Stabilized Alpha Helix Cell Surface Display: Protein Engineering and Linker Chemistry to Improve Intracellular Delivery and Whole Animal Pharmacokinetics - Greg Thurber |
| 9:25 AM |
9:40 AM |
Engineering Cell-Penetrating Peptides for Translocation into Candida Fungal Pathogens - Amy J. Karlsson |
| 9:40 AM |
9:55 AM |
Treating MRSA Superbugs with Deimmunized Enzymes Engineered to Evade Immune Surveillance - Karl E. Griswold |
| 9:55 AM |
10:10 AM |
Inhibition of Cancer Immune Suppression with a First-in-Class Engineered Therapeutic Enzyme - John Blazeck |
| 10:10 AM |
10:40 AM |
Break |
| 10:40 AM |
11:10 AM |
Session 3: Metabolic Engineering for Fuels, Chemicals and Pharmaceuticals |
| 10:40 AM |
11:05 AM |
Invited Speaker: Enzyme Design and Screening to Facilitate Pathway Engineering - Kristala L.J.Prather |
| 11:05 AM |
11:20 AM |
Leveraging New Genome Editing Tools to Engineer Non-Traditional Yeasts for Chemical Biosynthesis - Ian Wheeldon |
| 11:20 AM |
11:35 AM |
A Generalizable Crispr-Cas9 System for Rapid and Scalable Gene Target Discovery and Optimization - Matthew H Deaner |
| 11:35 AM |
11:50 AM |
Engineering Robust Xylose Utilization in Yarrowia Lipolytica Using Cryptic Metabolic Pathways - Mark A. Blenner |
| 11:50 AM |
12:05 PM |
Developing Green Cell Factories: The Journey to Cyanobacterial Fuels and Chemicals - Christie A.M. Peebles |
| 12:05 PM |
12:20 PM |
Systems and Synthetic Biology of Rhodococcus Opacus to Enable Conversion of Lignin-Derived Aromatic Compounds into Lipids - Tae Seok Moon |
| 12:20 PM |
2:00 PM |
Lunch |
| 2:00 PM |
4:35 PM |
Session 4: Novel Synthetic Biology Tools and Applications |
| 2:00 PM |
2:25 PM |
Invited Speaker: Engineering Biological Computers for Human Health Applications - Timothy K. Lu |
| 2:25 PM |
2:40 PM |
Genome-Level Sequence to Function Mapping – a Systematic Approach for Discovery - Gur Pines |
| 2:40 PM |
2:55 PM |
Engineered Crispr-Cas9 Systems As Programmable Regulators for Gene Expression Using Cellular Information - Wilfred Chen |
| 2:55 PM |
3:10 PM |
Divide and Conquer: How Compartmentalization Leads to Enhanced Flux for Metabolic Pathways - Danielle Tullman-Ercek |
| 3:10 PM |
3:25 PM |
Rapid Prototyping of Expanded 6-Letter Genetic Codes - Javin P. Oza |
| 3:25 PM |
3:40 PM |
Noninvasive Imaging of Gene Expression Using Diffusion Altering Reporters - Arnab Mukherjee |
| 3:40 PM |
3:55 PM |
Microbial Biosynthesis of Terminal Alkynes and Applications - Xuejun Zhu |
| 3:55 PM |
4:10 PM |
Devices for Monitoring, Selectiion and Actuation on Cellular Processes - Michael K. Jensen |
| 4:10 PM |
4:35 PM |
Invited Speaker: Synthetic Regulation of Metabolic Pathways and Microbial Subpopulations - Fuzhong Zhang |
| 4:35 PM |
5:00 PM |
Break |
| 5:00 PM |
6:35 PM |
Session 5: Biosensors, Bionanotechnology, and Bioelectronics |
| 5:00 PM |
5:25 PM |
Invited Speaker: Lighting up Small Molecules with RNA-Based Fluorescent Biosensors - Ming Hammond |
| 5:25 PM |
5:50 PM |
Invited speaker: Computational Design of Peptides That Bind to Specific Biomolecule Targets - Carol Hall |
| 5:50 PM |
6:05 PM |
Yeast-Based Biosensors As a Low-Cost Healthcare Diagnostic - Keith E.J. Tyo |
| 6:05 PM |
6:20 PM |
Real-Time Measurement of Therapeutic Drugs in Living Subjects: Making Personalized Drug Therapy a Reality - Netz Arroyo-Curras |
| 6:20 PM |
6:35 PM |
Designing Highly Specific Protein-Based Small Molecule Biosensors - Srivatsan Raman |
| 6:35 PM |
6:50 PM |
GPCR-Based Sensors to Accelerate the Engineering of Chemical-Producing Microbes - Pamela Peralta-Yahya |
| 7:00 PM |
9:00 PM |
Dinner and Keynote: Tiny Technologies and Medicine: From Hepatic Tissue Engineering to Cancer Nanotechnology - Sangeeta Bhatia |
| 7:00 AM |
12:00 PM |
Registration |
| 7:45 AM |
8:15 AM |
Breakfast |
| 8:15 AM |
10:10 AM |
Session 6: Metabolic Engineering for Fuels, Chemicals and Pharmaceuticals |
| 8:30 AM |
8:55 AM |
Invited Speaker: Static and Dynamic Transcription Engineering of Metabolic Fluxes in E.coli For the Production of High Value Chemicals - Mattheos A. G. Koffas |
| 8:55 AM |
9:10 AM |
Engineering Cyanobacteria for Use As Photosynthetic Chemical Factories - Brian F. Pfleger |
| 9:10 AM |
9:25 AM |
Eliminating Lactic Acid, an "Essential" Contaminant Limiting Biopharmaceutical Production - Nathan Lewis |
| 9:25 AM |
9:40 AM |
Orthogonal Design of Metabolic Pathways - A. Vikram Pandit |
| 9:40 AM |
9:55 AM |
Meta-Analysis of -Omics Level Data for Efficient Production of N-Linked Glycoproteins in a Bacterial Host - Stephen R. P. Jaffé |
| 9:55 AM |
10:10 AM |
A Metabolic Engineering Approach to Realize Nitric Oxide-Potentiating Anti-Infectives - Mark P. Brynildsen |
| 10:10 AM |
10:40 AM |
Break |
| 10:40 AM |
12:20 PM |
Session 7: Biomolecular Engineering Applications: Therapeutics, Diagnostics and Imaging Agents |
| 10:40 AM |
11:05 AM |
Invited Speakers: Development of an Anti-Pertussis Immunotherapeutic Antibody - Jennifer A Maynard |
| 11:05 AM |
11:20 AM |
Episcope: Computationally-Driven Identification of Antibody Epitopes - Casey Hua |
| 11:20 AM |
11:35 AM |
DIY Detection of a Wide Range of Biological Analytes with a Re-Engineered Glucose Sensor - Jeroen De Buck |
| 11:35 AM |
11:50 AM |
Reshaping the Immune Response with Engineered Interleukin-2 Antibodies - Jamie B. Spangler |
| 11:50 AM |
12:05 PM |
Using Conformationally Dynamic Beta Roll Peptides to Control Engineered Protein Functions - Scott Banta |
| 12:05 PM |
12:20 PM |
Analyzing, Predicting, and Engineering Antibody Responses - Sai Reddy |
| 12:20 PM |
2:00 PM |
Lunch |
| 2:00 PM |
3:45 PM |
Session 8: Cellular and Tissue Engineering and Biomaterials |
| 2:00 PM |
2:25 PM |
Invited Speaker: Developing Hydrogels to Control Microvasculature Assembly - Sharon Gerecht |
| 2:25 PM |
2:40 PM |
The Role of Cancer Cell Force Transmission on Sensing Structural and Mechanical Features of Contact Guidance Cues - Ian Schneider |
| 2:40 PM |
3:05 PM |
Invited Speaker: An Engineering Approach to Investigate Niche Regulation of Hematopoietic Stem Cell Fate - Brendan Harley |
| 3:05 PM |
3:20 PM |
Turning Lemons into Lemonade: Engineering T Cells that Resist and Convert Immunosuppressive Tumor Microenvironments - Yvonne Chen |
| 3:20 PM |
3:45 PM |
Invited Speaker: Dynamically Stiffening Matrices Promote Malignant Transformation Via Collective Mechanical Signaling - Adam Engler |
| 3:45 PM |
4:15 PM |
Break |
| 4:15 PM |
5:00 PM |
Keynote: A Genetic Toolkit for the Synthesis and Assembly of Materials and Devices for Energy, the Environment and Medicine - Angela Belcher |
| 5:00 PM |
8:00 PM |
Rapid Fire Presentation and Poster Session |
| 7:00 AM |
12:00 PM |
Registration |
| 7:30 AM |
8:00 AM |
Breakfast |
| 8:15 AM |
10:50 AM |
Session 9: Experimental and Computational Tools for Designing and Engineering Biomolecules and Biosystems |
| 8:15 AM |
8:40 AM |
Invited Speaker: Engineering Polymerases By Directed Evolution - Andrew Ellington |
| 8:40 AM |
8:55 AM |
Integrated Chemical and Genetic Approach for Programmable Crispr-Cas Delivery - Prashant Mali |
| 8:55 AM |
9:10 AM |
High throughput tools for rationally engineering regulatory RNAs - Lydia M. Contreras |
| 9:10 AM |
9:25 AM |
Multiplexing with the Class 2 Crispr Effector Protein Cpf1 - Chase L. Beisel |
| 9:25 AM |
9:40 AM |
Modeling and Analysis of a Cell-Free Glycoprotein Production in Escherichia coli - Jeffery D. Varner |
| 9:40 AM |
9:55 AM |
Using a Genome-Scale Model and Genomic Library to Discover the Functions of Metabolic Genes - Jennifer L. Reed |
| 9:55 AM |
10:25 AM |
Break |
| 10:25 AM |
10:40 AM |
Improving Synthetic Metabolic Pathway Yields and Productivities Using a Hybrid Computational/Experimental Approach to Increase Enzyme Solubility - Tim Whitehead |
| 10:40 AM |
10:55 AM |
High-Throughput Screening of Membrane Transport Proteins in Synthetic Lipid Vesicles - Philip A. Romero |
| 10:55 AM |
11:20 AM |
Invited Speaker: Bottom-up Construction of Microbial Consortia Inspired By Nature - Michelle O'Malley |
| 11:20 AM |
12:05 PM |
Keynote Speaker: Revealing Proteometrics Through Advanced Laboratory Evolution - Bernhard Palsson |
| 12:05 PM |
12:20 PM |
Closing Remarks and Awards |
