(334bf) Ex Vivo Minigut Mucosal Model for Development of New Oral Vaccine
AIChE Annual Meeting
2020
2020 Virtual AIChE Annual Meeting
Meet the Candidates Poster Sessions
Meet the Industry Candidates Poster Session: Pharmaceutical Discovery, Development and Manufacturing Forum
Tuesday, November 17, 2020 - 8:00am to 9:00am
In this study, we successfully built a model for mimicking intestinal mucosal system for testing drug delivery. For this project, Intestinal stem cells was used, and Microfold cells were first differentiated by using 200 ng/ml RANKL,later on, this result were confirmed by different methods, which including qPCR, immuno-staining and western blot. Gold Nanocage was used for modeling drug transportation. In the future study, sigma 1 protein will be linked to gold Nanocage, making the Nanocage an idealistic nanomaterials for transporting antigen through M cells to tiger immune responses. 
Topics
Checkout
This paper has an Extended Abstract file available; you must purchase the conference proceedings to access it.
Do you already own this?
Log In for instructions on accessing this content.
Pricing
Individuals
| AIChE Pro Members | $150.00 |
| AIChE Emeritus Members | $105.00 |
| AIChE Graduate Student Members | Free |
| AIChE Undergraduate Student Members | Free |
| AIChE Explorer Members | $225.00 |
| Non-Members | $225.00 |