(504b) Innovating Biomaterials Design for Precision Medicine in Biosensing

Precision medicine is an emerging approach that matches patients with the most appropriate treatment based on the precise molecular features of an individual patient’s disease. Despite huge advances in translational research, diagnosis and treatment continue to pose profound challenges in addressing significant health problems, including cancer and infectious diseases. In this talk, I will discuss a project that demonstrate molecular engineering efforts toward precision medicine. The project focuses on new development in point-of-care diagnosis: multiplexed analyses of multiple analytes predictive of impending sepsis based on hydrogel-based arrays combined with computational holographic imaging method. These studies highlight the potential of integrating chemical engineering, electrical engineering and clinical science approaches to develop advanced diagnostics and innovative therapies for precision medicine.