(495g) Membrane Assisted Reactive Crystallization with Multiple Interfacial Flow Regimes for Effective Mass Transfer Control

Reactive crystallization is an important technology for the preparation of the advanced micro/nano materials. The mixing and diffusion processes between the reaction solutions play a vital role in the crystal nucleation and growth. While, the interfacial area and mass transfer condition are commonly limited by the conventional crystallization kettle with complicated and insufficient three-dimensional mixing flow filed, resulting undesired quality in the crystal products.

Herein, membrane-assisted reactive crystallization (MARC) with effective interfacial flow regimes was proposed to achieve the effective mass transfer control during reactive crystallization. Three tube-shell side solution systems (EtOH-H₂O, Butanol-H₂O and H₂O-H₂O) have been chosen to form different two dimensional flow regimes on the membrane surface, including the microscale liquid layer and the uniform droplets. Real-time observation method was utilized to investigate the formation and the control of the liquid layer, and the invertible transform between the droplets and the liquid layer. With the established force analysis model, the motion of the droplets on the membrane surface and the transform mechanism between the droplets and liquid layer were systematically illustrated. The molecular dynamics simulation of the reactive ions diffusion coefficients in the three solution systems demonstrated that the membrane assisted reactive crystallization (MARC) can provide various diffusion conditions by regulating the flow regimes. A wide crystal size (700 nm to 3 μm) with uniform size distribution can be effectively obtained via MARC. MARC exhibits excellent performance for the regulation of the diffusion and mixing processes, which shed light on effective mass transfer control and advanced crystal materials manufacture during reactive crystallization.