Marianne Rots studied Medical Biology at the University of Amsterdam, obtained her PhD at the VU Medical Center, Amsterdam in 2000 and was subsequently trained as postdoctoral fellow in the Gene Therapy Center of the University of Alabama, Birmingham, USA. In 2001, she was recruited to the School of Pharmacy in Groningen and in 2007 to the University Medical Center Groningen, to start her own research group. She combined gene therapy and epigenetics and was one of the first to establish Epigenetic Editing, for which she obtained several prestigious grants. In 2010, she was appointed professor of Molecular Epigenetics in the Department of Pathology and Medical Biology at the University Medical Center in Groningen. So far, thirteen PhD students graduated (of with two with the highest distinction) under her supervision. Among others, she also serves as co-chief editor of Nature Springer’s Clinical Epigenetics, acts as research coordinator of an H2020-EU-ITN consortium (www.epipredict.eu) and is vice-chair in a EU COST action (CM1406: www.epichembio.eu).