Yonatan Stelzer received his PhD from the Hebrew University of Jerusalem Israel. His PhD work focused on studying the roles of parental imprinting during early human embryogenesis and in disease conditions, using human embryonic and induced pluripotent stem cells. In 2014, Yonatan joined the laboratory of Prof. Rudolf Jaenisch at the Whitehead Institute of MIT USA, as a postdoctoral fellow. In his postdoctoral work, Yonatan pioneered a reporter system that allows monitoring real-time changes of DNA methylation in single cells, both in vitro and in vivo, while facilitating prospective isolation of cells based on their methylation signature. Recently, Yonatan joined the faculty at the Weizmann Institute of Science Israel. His laboratory utilizes the mouse as a model organism and combine genome- and epigenome-editing tools, together with single cell genome-wide approaches, to study the functional roles of DNA methylation in development and disease