Advances in Protein Structure, Function, and Stability I

This session seeks submissions in the areas of experimental, theoretical, and computational approaches to rational prediction, design, and/or optimization of protein structure, stability, and function in laboratory and processing settings relevant to biopharmaceutical products in general. Studies may include structural analysis and engineering of proteins, creation or optimization of function, thermodynamics and dynamics of protein conformational stability, issues in folding or misfolding, degradation via physical and chemical routes, or related concerns in intracellular expression and refolding, purification, and final product formulation. Preference will be given to papers dealing with strategies that are relevant to commercial and biological systems and also provide insights into the molecular pathways or mechanisms controlling behavior.