Advances in Systems Biology: Computational Methods and Applications

Developments in high throughput technologies have allowed for rapid improvement of many biological species and systems including enzymes, protein complexes, cellular pathways and whole organisms. The current challenge is how to apply these technologies for enabling discoveries in many diverse areas of biochemical technology such as metabolic engineering, drug discovery, tissue engineering, and bioprocess development. This session will include contributions that describe applications of existing technologies (e.g. directed evolution, genomic and proteomic information in cellular and metabolic engineering), improvement and development of new technologies and methodologies (e.g. new combinatorial display techniques, improvements in proteome and transcriptome technologies), and computational and mathematical frameworks for the quantitative analysis of the available information (e.g. computational approaches to library construction and prescreening, systems engineering application on biological systems, computational methods for prediction of protein structure and function).