Protein Chromatography and Chiral Resolution of Biomolecules

Conference

AIChE Annual Meeting

Year

2005

Proceeding

2005 Annual Meeting

Group

Bioseparations

Type

Oral

Room

Wolverine AB

Location

Hyatt Regency Cincinnati

Time

Thursday, November 3, 2005 - 12:30pm to 3:00pm

Chair(s)

Cramer, S., RPI

Co-chair(s)

Kuehne, J., Bristol-Myers Squibb

The focus of this session is to identify the latest theoretical and experimental advances in the use of chromatography for protein purification. Applications can range from large scale manufacturing to microscale proteomic applications. Topics to be covered will include, but are not limited to: Affinity chromatography, Ion exchange chromatography, Hydrophobic chromatography, Simulated moving bed chromatography, membrane chromatography, multidimensional chromatography and chip based systems.

Presentations

12:30 PM

(523a) Cartridge Filter Separation System: an Alternative to Column Chromatography in Downstream Purification of Protein Therapeutics

12:50 PM

(523b) Functionalized Nanoporous Molecular Sieves for Chromatographic Separations of Proteins

1:10 PM

(523c) Protein C Purification Using Pc Specific Mini-Mab from the Inexpensive Source, Cohn Blood Plasma Fraction VI-1

1:30 PM

(523d) Investigation of Protein Adsorption and Similarity Measurement for Protein Binding Behavior in Hydrophobic Interaction Chromatography (Hic) System

1:50 PM

2:00 PM

(523e) Resolution of Racemic Mixtures Coupling Crystallization and Simulated Moving Bed: Fundamental Studies for S-Ketamine Production

2:20 PM

(523f) Mutants of Phenylalanine Dehydrogenase: New Bio-Catalysts in the Asymmetric Synthesis and Racemic Resolution of Non-Natural Aminocids

2:40 PM

(523g) Molecular Mechanisms of Selective Sorption of Chiral Enantiometers on Amylose-Based Sorbents

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