(369e) Is It Del B, or Del B^2? That Is the Question | AIChE

(369e) Is It Del B, or Del B^2? That Is the Question

Authors 

Chalmers, J. J. - Presenter, The Ohio State University
Zborowski, M. - Presenter, Cleveland Clinic Foundation
Sun, J. - Presenter, The Ohio State University
Zhao, Y. - Presenter, The Ohio State University


The Zborowski and Chalmers lab have been advocating the use of magnetophoretic mobility as a means to both characterize the degree to which a cell is immunomagnetic labeled as well as a means to design, operate, and analyze the performance of immunmagnetic cell separation systems. A common criticism/concern of our method of calculating magnetophoretic mobility is the use of the magnetic energy gradient calculated as Del B^2 instead of Del B.

In this presentation we will present our experimental studies with our modified electromagnetic CTV system which allows us to vary the value of B over and order of magnitude. This allows for the direct answering of the question: Is the magnetophoretic mobility constant as Del B^2 changes? We will present experimental evidence that based on the material and value of B, both sides in the debate are correct.