(187b) Glucose Sensor Using Non-Woven Single-Wall Carbon Nanotube Films

Diabetes is a metabolic disorder and a major world health problem. There are over 170 million diabetics worldwide and the number is projected to 300 million in 2025, so glucose sensors are becoming incredibly important. In this work we report novel glucose sensor using non-woven SWNT film synthesized directly by chemical vapor deposition (CVD) and GOx as a sensing element. The SWNT film shows excellent mechanical properties and can be used as nanomaterials for GOx immobilization. The catalytic reduction of hydrogen peroxide and gluconolactone generated from the enzymatic reaction was observed at very low applied potential of -0.1 V (vs. Ag/AgCl) and led to the selective detection of glucose with very high sensitivity, a fast response time of less than 10 s and a limit of detection (LOD) of 0.05 mM. At such low applied potential, the interference from common interfering agents such as uric acid and ascorbic acid can be minimized. These results indicate that the non-woven SWNT film is a promising material for constructing biosensors.