(517s) Intraoperative Treating of Abdomenal Cavity by Preparation at-31

Affectivity of the intra-operative treating of abdominal cavity by preparation AT-31 in patients with peritonitis was studied. Considerable reduction of microbe's quantity on the surface of peritoneum after its intra-operative treating by the preparation AT-31 plays main role in the detoxification of organism. Decreasing of pathogenic activity of microbes under influence of preparation AT-31 is important, because even after the careful lavage of abdominal cavity the considerable quantity of microbes will stay on the surface of peritoneum, in ideal thermostatic circumstance. Suppression of toxicity of microbes left in abdominal cavity promotes the improvement of efficiency of detoxification and antibacterial therapy. For the stimulation of reactivity of organism is very important increasion of phagocytic activity of neutrophils after intra-operative treating of abdominal cavity of patients by the preparation AT-31. Morphological investigations showed, that preparation AT-31 hinders the penetration of infection depth in tissue. Morphological investigations showed that after intra-operative treating of abdominal cavity by the preparation AT-31, the processes of reparation begin on 4-5 days earlier then in the control. In the group of observation revealed less percent of postoperative complications then in control. The efficiency of method of intra-operative treating of abdominal cavity by the preparation AT-31 also was proved with lowering of duration of hospitalization period. It must be mentioned that the effect was more expressed in the toxic and terminal phases of disease. It is very important that the lethality of patients, as in toxic as in terminal phases of peritonitis, was lower in the group of observation.