(144b) The Design and Scale-up of An API Crystallization: Process Understanding Supported by Modeling to Achieve Consistency
AIChE Annual Meeting
2008
2008 Annual Meeting
Pilot Plant Centennial Celebration - Sponsored by Group 12b, Pilot Plants
Data Mining and Modeling of Unit Operations - Sponsored by Group 12b, Pilot Plants
Monday, November 17, 2008 - 3:45pm to 4:10pm
An API crystallization was designed on bench scale with a knowledge of process thermodynamics, and scaled-up and interpreted using both empirical and semi-empirical models. This scale-up approach resulted in both process consistency and predicability.