(572l) Coupling Hemodynamics and Protein Regulation In Cerebral Saccular Aneurysms | AIChE

(572l) Coupling Hemodynamics and Protein Regulation In Cerebral Saccular Aneurysms

Authors 

Rafat, M. - Presenter, Harvard University
Heller, M. - Presenter, Technical University of Denmark
Stone, H. A. - Presenter, Princeton University
Auguste, D. T. - Presenter, School of Engineering and Applied Sciences, Harvard University


The mechanisms behind aneurysm growth and rupture are unknown. Additional analysis of the relationship between hemodynamics, mechanical forces, and biological response may enable aneurysm prediction, improve diagnosis, and allow development of new treatment approaches. We examined the hemodynamic profiles of clinically relevant aneurysm geometries for a range of physiological Reynolds numbers (100