(602c) Eulerian Particle Tracking in Bifurcating Biofluids
AIChE Annual Meeting
2008
2008 Annual Meeting
Computing and Systems Technology Division
Mathematical and Computational Biosystems Engineering I
Thursday, November 20, 2008 - 9:10am to 9:30am
Biofluid flows in bifurcating geometries has become paramount to the medical community. When addressing inhaled particulate matter in the lungs, it is essential to have an efficient computational model. High-order elements offer the opportunity to model nanoparticle deposition in a case by case basis with moderate computer processor times. This adds insight into cancer precipitation as well as an advantageous route to designing patient specific therapeutic aerosols. This study focuses on developing high-order methods for particle tracking in the weakly turbulent flows that are common in the biological setting. High-order elements are used for direct numerical simulation in the incompressible fluid flow to fully resolve the transporting field. The advection-diffusion is then solved with similar methods to predict a deposition of passive and dilute particles. Eulerian-Eulerian particle tracking has shown a route to developing drug delivery on an individual basis with moderate computing times. The quick adaptation and interpolation between meshes offers a promising perspective that lends towards the utilization in the medical community. The scientific code, Nek5000, and the computer cluster at Arizona State University is used to demonstrate the effectiveness of the field method. Experiments at University of Arizona lend validation to the models. Future work in biological particle tracking will hinge upon the community's abilities to adapt to high-order methods in an efficient manner.
Checkout
This paper has an Extended Abstract file available; you must purchase the conference proceedings to access it.
Do you already own this?
Log In for instructions on accessing this content.
Pricing
Individuals
AIChE Pro Members | $150.00 |
AIChE Graduate Student Members | Free |
AIChE Undergraduate Student Members | Free |
AIChE Explorer Members | $225.00 |
Non-Members | $225.00 |