(397a) Expect the Unexpected - Introducing Uncertainty in the Chemical Engineering Laboratory

The evolution of Chemical Engineering imposes a unique challenge to the design of adequate modules in the laboratories. The constant design and manufacture of new chemical products is characterized by fast-paced product and process development. This requires that engineers and managers work under highly uncertain scenarios. We have designed and implemented a novel experimental module in the Chemical Engineering laboratory that intentionally exposes the students to high uncertainty. The module also includes contemporary topics in colloids, complex fluids and biotechnology, thus also giving more emphasis to molecular interactions. The objective of this quarter-long project is the extraction of lysozyme from egg whites. Students use Aqueous Bi-Phasic Systems (ABS) in three separate experimental phases that range from benchtop to pilot scale experiments. During the first phase, students optimize the separation of lysozyme from ovalbumin using bench scale extractions. In the second phase, students scale the separation to the pilot scale using a reciprocating liquid-liquid extraction column. In the third phase, students optimize the process and perform the final extraction of lysozyme from egg whites. Students in each phase review scientific literature and reports from the other groups. This emphasizes the value of adequate critical reviews of literature and reports from peers. Our goal is to help students develop "soft" skills such as composure, critical thinking, creativity, group work, task division, time management and forward thinking. We are intentionally exposing the students to high degrees of uncertainty which serves as a tool to prepare the students for a rapidly changing industrial world.