(704a) Nanotechnology for Tissue Engineering: A State of the Art Review

This review will summarize studies which have demonstrated enhanced in vitro and in vivo tissue growth on nanostructured metals, ceramics, polymers, and composites thereof compared to currently-used implants. Tissue growth to be emphasized will consist of bone, cartilage, vascular, skin, bladder, nervous system, and other tissues. These results strongly imply that nanomaterials may improve tissue regeneration compared to what is being implanted today. This review will also focus on a fundamental explanation why tissue growth is enhanced on nanostructured compared to conventional tissue engineering materials summarizing a wide range of research efforts, including those which have already received FDA approval for implantation. Thoughts on the necessary future studies for the field of nanotechnology and tissue engineering to progress will also be presented.