(697d) Mixture DOE and Design Space
AIChE Annual Meeting
2010
2010 Annual Meeting
Comprehensive Quality by Design in Pharmaceutical Development and Manufacture
Model Based QbD in Drug Substance or Drug Product
Thursday, November 11, 2010 - 4:15pm to 4:35pm
Present a case study on mixture DOE involving five components used to formulate a pharmaceutical tablet. The goal is to achieve a sustained release by optimizing the concentration of a hydrophilic polymer in relation to the proportions of a drug and three excipients. Four responses (two related to release) are measured and modeled. Then numeric and graphical optimization are used to define a design space.
Checkout
This paper has an Extended Abstract file available; you must purchase the conference proceedings to access it.
Do you already own this?
Log In for instructions on accessing this content.
Pricing
Individuals
2010 Annual Meeting
| AIChE Pro Members | $150.00 |
| AIChE Graduate Student Members | Free |
| AIChE Undergraduate Student Members | Free |
| AIChE Explorer Members | $225.00 |
| Non-Members | $225.00 |
Comprehensive Quality by Design in Pharmaceutical Development and Manufacture only
| AIChE Pro Members | $100.00 |
| Food, Pharmaceutical & Bioengineering Division Members | Free |
| AIChE Graduate Student Members | Free |
| AIChE Undergraduate Student Members | Free |
| AIChE Explorer Members | $150.00 |
| Non-Members | $150.00 |