(602e) Interaction Between An Elastic Filament and the Vesicle Membrane | AIChE

(602e) Interaction Between An Elastic Filament and the Vesicle Membrane

Authors 

Young, Y. - Presenter, New Jersey Institute of Technology
Jacobs, C. - Presenter, Columbia University


The primary cilium is found for all non-dividing mammalian cells. Since its discover
a century ago, only recently has more understanding of the biological role
of primary cilia been gained.  In this work slender-body formulation is utilized to
describe the dynamics of the primary cilium, modeled as an elastic filament attached
to a solid wall or membrane. Comparison with the experimental data will be provided.
Coupling between the filament/membrane system and the mechanosensitive channel (MscL)
show how the primary cilium functions as a probe of the extracellular flow.