(602e) Interaction Between An Elastic Filament and the Vesicle Membrane
AIChE Annual Meeting
2011
2011 Annual Meeting
Engineering Sciences and Fundamentals
Novel Numerical Methods In Fluids
Wednesday, October 19, 2011 - 4:55pm to 5:20pm
The primary cilium is found for all non-dividing mammalian cells. Since its discover
a century ago, only recently has more understanding of the biological role
of primary cilia been gained. In this work slender-body formulation is utilized to
describe the dynamics of the primary cilium, modeled as an elastic filament attached
to a solid wall or membrane. Comparison with the experimental data will be provided.
Coupling between the filament/membrane system and the mechanosensitive channel (MscL)
show how the primary cilium functions as a probe of the extracellular flow.