(155a) Invited Talk: A Review of the Use of Nanotechnology in Tissue Engineering

Inspired from biological systems, nanotechnology is beginning to revolutionize medicine including improving the prevention, diagnosis, and treatment of numerous diseases. This talk will summarize efforts over the past decade that have synthesized novel nanoparticles, nanotubes, and other nanomaterials to improve medicine. Efforts focused on the use of nanomaterials to minimize immune cell interactions, inhibit infection, and increase tissue growth will be especially emphasized. Tissue systems covered will include the nervous system, orthopedics, bladder, cardiovascular, vascular, and the bladder. Due to complications translating in vitro to in vivo results, only in vivo studies will be emphasized here. Materials to be covered will include ceramics, metals, polymers, and composites thereof. Self-assembled nano-chemistries will also be emphasized. As the FDA has now approved several nanomaterials for medical applications, recent results from FDA trials will also be discussed. In summary, this talk will provide the latest information concerning the design and use of numerous nanomaterials in regenerative medicine while highlighting what is necessary for this field to continue to grow.