(594g) The Role of Simulation and Scheduling Tools in Bioprocess Development and Manufacturing
AIChE Annual Meeting
2012
2012 AIChE Annual Meeting
Food, Pharmaceutical & Bioengineering Division
Food and Bioprocess Engineering Poster Session
Wednesday, October 31, 2012 - 6:00pm to 8:00pm
The successful scale up and commercialization of biopharmaceuticals, bio-fuels and biomaterials is a challenging task that requires collaboration of professionals from many disciplines. Process simulators and other computer aids can facilitate this task by assisting scientists and engineers to answer the following and other related questions: What is the impact of product titer increase on the capacity load of the downstream section, the overall throughput of a plant, and the cost of goods? What changes are required in an existing multi-product facility to accommodate the process of a new product? What is the range of variability that a process can accommodate if it operates under a tight cycle time? What is the impact of single-use systems on the demand for utilities, the environment and the cost of goods? Our experience in addressing the above questions will be presented using industrial examples in which we evaluated alternative technologies for producing therapeutic monoclonal antibodies, vaccines, second generation bio-fuels and commodity bio-chemicals.
See more of this Session: Food and Bioprocess Engineering Poster Session
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture