(522f) Salidroside Separation By Magnetic Polysulfone Microcapsules Containing Tributyl Phosphate

The active ingredients of Tibetan Rhodiola are salidroside and tyrosol determined by the HPLC method. Different extractants, such as tributyl phosphate (TBP) and N-octanol ,and the change of pH were investigated to recover the main component in the Rhodiola extract. A new method was developed for the salidroside separation from Rhodiola rosea by using magnetic polysulfone (PSF) microcapsules containing Fe₃O₄ particles and tributyl phosphate (TBP) (TBP/Fe₃O₄@PSF microcapsules) in this manuscript. The magnetic polysulfone microcapsules were prepared based on the phase-inversion method, and characterized by using Scanning Electron Microscopy (SEM), Infrared Spectroscopy (IR), Thermal Gravimetric Analysis (TGA) and Vibrating Sample Magnetometer (VSM). Magnetic microcapsules could provide easier separation in the external magnetic field. Results showed that salidroside could be separated from aqueous solution at pH 8.0. After three cycles, the magnetic microcapsules had almost the same extraction performance. These novel magnetic microcapsules have potential applications in the separation and purification of natural products.