(585ad) Spray Drying of Uniform Microparticles for Encapsulation and Controlled Release

The Biotechnology and Food Engineering group at Monash University has developed a low temperature assembly approach to synthesise monodisperse microparticles in a scalable, waste-free process, stemming from their research on thermal sensitive dairy powders. Using a microfluidic jet spray drying method, functional particles with uniform properties, including fluorescent and magnetic composites, polymeric microparticles for encapsulation and controlled release, and mesoporous microspheres, can be synthesised. The fabrication route is applicable to other self-assembling systems and could be a cost effective, energy and material-efficient route to produce bioactive powders with potential technology transfer to functional foods and therapeutics industry. The talk will give an overview of this assembly method with examples of several applications, and the view to invite future collaboration opportunities.

Related publications:

1.     Liu, W., Wu, W., Selomulya, C.*, Chen, X. D., 2013, On designing particulate carriers for encapsulation and controlled release applications, Powder Technology, 236, 188-196.

2.     Liu, W., Wu, W., Selomulya, C.*, Chen, X. D., 2012, Spray drying of monodispersed microencapsulates: implications of process parameters on microstructural properties and controlled release functionality, Journal of Microencapsulation, 29: 7, 677-684.

3.     Rogers, S., Fang, Y., Lin, S., Selomulya, C., Chen, X. D., 2012, A Monodisperse Spray Dryer for milk powder: Modelling the formation of insoluble material, Chemical Engineering Science, 71, 75-84.

4.     Liu, W., Wu, W., Selomulya, C.*, Chen, X. D. 2011, Facile spray-drying assembly of uniform microencapsulates with tunable core-shell structures and controlled release properties, Langmuir, 2011, 27 (21), pp 12910–12915.

5.     Wu, W., Liu, W., Selomulya, C., Chen X. C., 2011, On Spray Drying of Uniform Silica-Based Microencapsulates for Controlled Release, Soft Matter, 7, 11416-11424.

6.     Fang, Y., Rogers, S., Selomulya, C.*, Chen, X. D., 2011, Functionality of milk protein concentrate: Effect of spray drying temperature, Biochemical Engineering Journal, Volume 62, 101-105.

7.     Liu, W., Wu, W., Selomulya, C.*, Chen, X. D., 2011, A single step assembly of uniform microparticles for controlled release applications, Soft Matter, 7, 3323 - 3330.

8.     Wu, W., Amelia, R., Hao, N, Selomulya, C., Zhao, D., Chiu, Y., Chen, X. D., 2011, Assembly of Uniform Photoluminescent Microcomposites Using a Novel Micro-Fluidic-Jet-Spray-Dryer, AIChE Journal, 57:10, 2726–2737.

*: C. Selomulya as the corresponding author