Solid Form Selection: Cocrystals, Salts, Solvates, Polymorphs, and Beyond | AIChE

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Solid Form Selection: Cocrystals, Salts, Solvates, Polymorphs, and Beyond

Chair(s)

Sweeney, J., Bristol-Myers Squibb

Co-chair(s)

Nagy, Z. K., Purdue University

Continuous improvement of the physicochemical properties of active pharmaceutical ingredients (APIs) such as solubility, bioavailability, dissolution rate, stability, hygroscopicity, crystallinity and taste, represents an emerging area of research and development. This session focuses on the selection of solid forms including cocrystals, salts, solvates and polymorphs in crystallization processes, as well as the screening, predicting, manipulating and controlling techniques for such product selection.

Presentations

12:30 PM
Introductory Remarks
12:35 PM
(707a) Microfluidic Platform for Cocrystal Screening and Characterization
12:55 PM
(707b) Identification and Crystallization Development of Potential Conformational Polymorphs of an Active Pharmaceutical Ingredient
1:15 PM
(707c) Depiction and Prediction of Practical Pathways for Crystallization
1:35 PM
(707d) Tailoring Polymorphism of Ortho-Aminobenzoic Acid (OABA) Using Combinations of Several Solvents and a Structurally Related Additive
1:55 PM
(707e) Crystallization of Valnemulin Hydrochloride Heterosolvate: Crystal Structure, Desolvation Behavior, Solubility and Nucleation Mechanism
2:15 PM
(707f) Polymorphism in Dabigatran Etexilate Mesylate: Nucleation and Transformation

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Individuals

AIChE Pro Members $150.00
AIChE Graduate Student Members Free
AIChE Undergraduate Student Members Free
AIChE Explorer Members $225.00
Non-Members $225.00

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