(15j) Protein Self-Assembly Toward Engineering of Biofunctional Nanomaterials
AIChE Annual Meeting
2016
2016 AIChE Annual Meeting
Meet the Faculty Candidate Poster Session – Sponsored by the Education Division
Poster Session: Meet the Faculty Candidate - Nanoscale Science & Engineering
Sunday, November 13, 2016 - 1:00pm to 3:30pm
Naturally-derived or artificially designed protein motifs present characteristic structural and physical properties, which can be harnessed to design self-assembling modules. For examples, modular combination of protein motifs results in self-assembly of protein suprastructures with various morphologies which include spheres [1], vesicles [2], sheets, porous structures [3], and artificial nano-shapes that are unprecedented in nature. I previously demonstrated protein self-assembly approaches using simple protein motifs such as coiled coils, elastin-like polypeptides, and artificial random coils. I will present protein assembly strategies to retain both self-assembled morphology and biological functionality of protein nanomaterials. To incorporate biological functionality, I will develop functional protein modules. In combination with computational design of protein structures, experimental characterization to engineer self-assembly processes and biological functionality will be discussed. In addition, I will present design strategies that relate nanostructural characteristics and specific applications.
Teaching Interests: At the graduate level, I plan to design a class for protein nanomaterials, which is at the interface between protein engineering and nanotechnology. While I provide knowledge about fundamentals of protein engineering, biochemistry, and nanotechnology, I will focus on teaching students to develop their ability to solve engineering problems in the interdisciplinary area. Also, I am interested in teaching undergraduate chemical engineering classes, using examples of biological systems at the nanoscale. My research background on protein self-assembly covers topics in chemical engineering, such as thermodynamics and kinetics of biomolecules. I would like to introduce examples of engineering problems in bio- and nanotechnology.
[1] W. M. Park and J. A. Champion, Angew. Chem. Int. Ed., 2013, 52, 8098-8101.
[2] W. M. Park and J. A. Champion, J. Am. Chem. Soc., 2014, 136, 17906-17909.
[3] W. M. Park, C. M. Yee, J. A. Champion, J. Mater. Chem. B, 2016, 4, 1633-1639.
Checkout
This paper has an Extended Abstract file available; you must purchase the conference proceedings to access it.
Do you already own this?
Log In for instructions on accessing this content.
Pricing
Individuals
AIChE Pro Members | $150.00 |
AIChE Graduate Student Members | Free |
AIChE Undergraduate Student Members | Free |
AIChE Explorer Members | $225.00 |
Non-Members | $225.00 |