(539f) Kinetic Study of Reactions of Aniline and Benzoyl Chloride in a Microstructured Chemical System

Kinetic Study of Reactions of Aniline and Benzoyl Chloride
in a Microstructured Chemical System

Peijian Wang, Kai Wang, Jisong Zhang, Guangsheng Luo^*

The State Key
Laboratory of Chemical Engineering, Department of Chemical Engineering,
Tsinghua University, Beijing 100084, China

Abstract

The reaction between aniline and benzoyl
chloride is well known for producing high performance polymers and chemicals.
But the fast main reaction and reversible consecutive side reaction make
process rather complicated and no thorough kinetics study has ever been
reported before. A microstructured chemical system, consisting
of a micromixer, pre-heat exchange coiled capillaries, a delay loop and a microhydrolyzer, was designed to carry out this
reaction in this study using NMP
as the solvent. A kinetic model was established, and the values of kinetic
constants, pre-exponential factors and activation energies of each reaction as
well as their confidence intervals were acquired. With this model each
substance concentration versus residence time were obtained to help understand
reaction process and further optimize operating conditions. Compared to earlier
reports on this reaction, this microstructured
chemical system provides more accurate parameters and can develop a reliable
platform for kinetic study of similar chemical reactions.

Keywords: kinetics; aniline; benzoyl chloride; NMP;
microstructured chemical