(421b) Area 15A Food Plenary Award - Efficient Biosynthesis of Microalgal DHA-Rich Oil: From Lab to Factory Scale

The Nutrient Chemicals are a number of chemicals with multiple functions which are important for good health, such as antioxidant, anti-radiation, improving memory, regulating blood lipid etc [1]. Our work is concentrated on one of lipid nutrient chemicals, docosahexaenoic acid (DHA). Docosahexaenoic acid is an important w-3 fatty acid, and contributes greatly to infant mental development and cardiovascular diseases prevention [2]. It has been widely used in food additives and pharmaceutical industries. The research work in our group mainly focused on how to realize the efficient DHA production by marine microorganism and improve the product quality. The detailed research work include strain improvement, nutrition and oxygen regulation, improvement of lipid quality, pathway modification, omics study and bioreactor design and scale up. We believe our work will be interested not only for those who focused on DHA-rich oil production, but also for the other nutrient chemicals related researchers.

Reference:

[1] REC Wildman. Handbook of nutraceuticals and functional foods, 2016, CRC press

[2] Agostoni C, Riva E, Trojan S, Bellu R, Giovannini M. Docosahexaenoic acid status and development quotient of healthy term infants. Lancet. 1995, 346(8975):638