(281d) Harnessing Power of Membranes to Enable Process Intensification and Improvement
AIChE Annual Meeting
2018
2018 AIChE Annual Meeting
Pharmaceutical Discovery, Development and Manufacturing Forum
Emerging Technologies in Pharmaceutical Research and Manufacturing
Tuesday, October 30, 2018 - 9:15am to 9:40am
Continuous processing in biopharmaceutical industry could be very well enabled by the appropriate application of continuous membrane technology, which has been used in its limited capacity.
The presentation will focus on the appropriate membrane selection and associated process design to not only the removal of the inorganic salts but also the undesired solvent and/or reagents. It will also delve in the engineering methodology to develop a membrane process and touch upon scale-up considerations and challenges for successful technology implementation in a cGMP chemical pilot plant setting.
Manish S. Kelkar, Daniel Weyant, Raja Reddy, John Bellettini, and Nandkishor K. Nere are employees of AbbVie. The design, study conduct, and financial support for this research was provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the publication.