(109g) Nano Field-Effect Transistor-Based Biosensors for Healthcare

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One- and two-dimensional nanomaterials are gaining growing interest in biosensors as they provide high sensitivity, multiplexing, small size and portability. Single walled carbon nanotubes (SWNTs), graphene and transition metal dichalcogenide (TMDC) are amongst such nanomaterial that exhibit superior sensing behavior due to their large surface atoms that are highly responsive to surface adsorption events. Combined with their compatibility with modern microfabrication technologies and facile functionalization with molecular recognition elements make them promising candidates for applications in biosensors for healthcare.

In this talk, I will present our recent research on SWNTs, graphene and Molybdenum disulfide nano field-effect transistor-based biosensors for healthcare. Field-effect transistors based on these 1D and 2D nanomaterials were functionalized with biological receptors such as antibodies, aptamers and binding proteins for highly sensitive, selective, rapid, cost-effective and point-of-care monitoring of bacterial and viral pathogens and biomarkers for acute myocardial infarction, psychosocial stress, blood glucose, etc. Further, these biosensors were integrated with paper microfluidics to realize the ASSURED criteria for diagnostics in resource-limited settings.