(269a) Interpretation of Impedimetric Signals of Biosensors

Over the past several years, our group has been developing soft matter dynamic surfaces to act as chemical and biosensors. One surface is a cyclodextrin mediated surface that decouples when exposed to an analyte. Another surface uses elastin-like polymer temperature response to look at different surface states. Shared in common is that these surfaces and sensor construction is no electrochemical mediator exists to clearly interpret a faradaic signal commonly seen in voltammetry or amperometry.

My group has been actively working with electrochemical impedance spectroscopy (EIS) to interpret the different dynamic surface states without an electrochemical mediator. We have been relying on interpreting the capacitive and the out-of-phase oscillating current response in the EIS signal. Within this talk we will provide a fundamental review of EIS, how It can be used to look at different surface states, and the current interpretation of our surfaces.

Support was provided by a National Science Foundation EPSCoR award (#2119237).