(2by) Harvesting Cultivated Meat Grown in a Bioreactor with a Low Shear Centrifuge. Centrifuge Is Either Single Use or CIP/Sip.
AIChE Annual Meeting
2023
2023 AIChE Annual Meeting
Meet the Candidates Poster Sessions
Meet the Faculty and Post-Doc Candidates Poster Session
Sunday, November 5, 2023 - 1:00pm to 3:00pm
"Cultivated" meat is created from undifferentiated animal stem cells, which are submerged in a nutrient-rich broth and induced to multiply along the paths suggested by a kind of structuring mold known as a scaffold. Much of the weeks-long process takes place inside bioreactors which replicate real life cell environments. After a couple weeks of growth, the cells need to be washed and harvested. Process parameters such as g force and feed flow rate determine to percent of recovery. The low shear single use centrifuges (UF Pilot family) in this study capture greater than 90 percent recovery of the cells. Its low/no shear design looses than 2 percent of the cells. The single use centrifuges- UFmini, UFpilot and U2K scale to one another. The UFmini sits on a bench and used in process development up to 50 liters. The UFpilot is for 50-1000 liter bioreactors, The u2k is for 500-5000 liter bioreactors. We also have CIP/SIP versions from the Viafuge family.