(376e) Antibacterial Properties and Catalytic Applications of Phosphazene-Based Covalent Organic Frameworks

Phosphazene-based covalent organic framework (COF) structures were prepared from the reactions of phosphonitrilic chloride, P₃N₃Cl₆ with multifunctional amines such as (tris(2-amino ethyl)amine (TAEA), pentaethylenehexamine (PEHA), branched polyethyleneimine (B-PEI), and poly(Vinyl amine) (PVAm)). The characterization of the prepared phosphazene-based COF structures were done via functional group and elemental analysis, morphological structures, sizes, surface areas, and the thermal stabilities. Because of the presence of amine and phosphazene groups that are considered to play major to render antibacterial properties, the prepared COFs antibacterial activities were tested against common microorganisms such as Escherichia coli (gram negative bacteria, ATCC 8739), Staphylococcus aureus (gram positive bacteria, ATCC 6538), and a yeast, Candida albicans (ATCC 10231) via disc diffusion and micro dilution techniques. Moreover, the potential use of the prepared COF structures as metal free catalyst in hydrogen (H₂) production from the dehydrogenation of sodium borohydride in methanol were investigated. The effect of amount of catalyst, concentration of NaBH₄, temperature on hydrogen generation rates (HGR) of catalyst were investigated and important activation parameters such as activation energy (Ea), enthalpy (ΔH), and entropy (ΔS) were calculated.

Acknowledgement

The authors are grateful for financial support from Canakkale Onsekiz Mart University Scientific Research Commission (COMU-BAP: FBA-2022-4166).