(473b) Applications of Dynamic Vapor Sorption in Characterizing Agrochemical Solids

Detailed solids characterization is crucial for optimization and troubleshooting the processes involving solids. An important property studied during characterization is the interaction of solids with the solvents present in the system or ambient humidity. This information guides decisions about processing, storage conditions, and handling techniques. Dynamic vapor sorption (DVS) is a useful technique to carry out such a characterization. In this technique, solvent molecules are used as a probe and sorption/desorption profiles are obtained. The nature of these profiles and/or the hysteresis between the two provide information about the type of interaction between the solid and the solvent under consideration. The interaction could result in absorption, surface adsorption, formation of hydrates or solvates, or other changes in the solid form. In this work, interaction between different agrochemical solids and water has been explored with the DVS instrument obtained from Surface Measurement System and the above-mentioned scenarios were identified. Additional characterization, such as particle size distribution, microscopy, and thermal analysis, were also carried out to better interpret the DVS results.