(255a) Sustainability Analysis Applied to Active Pharmaceutical Ingredient Manufacture

One of the concerns for drug manufacturing is sustainability parameters of the drug. There are many ways to produce drugs for pharmaceutical use. One way to produce a drug is by having microorganisms metabolize a certain compound and change the compound into the desired drug. Another route typically used is through organic synthesis. Manufacturing a drug is raw material and separation intensive and is an environment concern. The boundary of this study was a gate-to-gate analysis of the compounds along with data from the EIOLCA to provide a cradle to gate analysis of the compound. This paper provides a sustainability analysis of active pharmaceutical ingredients from data obtained from data obtained from patents and manufacturing sources. Trends and sustainability metrics that can be used by pharmaceutical companies will be described.