A new Laboratory using flow chemistry Techniques for continuous production of Pharmaceutical drugs– Case of PARACETAMOL | AIChE

A new Laboratory using flow chemistry Techniques for continuous production of Pharmaceutical drugs– Case of PARACETAMOL

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In order to answer to the need of patients, it is important to develop innovative solutions to produce new drugs with flexible manufacturing units. To be factual by using all disruptive innovations in different areas like intensification of process using continuous micro reactors controlled by PAT, Artificial Intelligence for retrosynthesis, Big data analysis, new materials of construction, microelectromechanical systems (MEMS), Internet of Things (IoT), 3D printing ...

This is the only way to relocate pharmaceuticals production which has been externalized to take advantage of local low manpower costs and regain our sovereignty

The new IPSOMEDIC’s lab installed in Aubagne (South in France), proposes the high quality right drug process with the right dose customized for each patient at low cost and safe conditions.

The main objective of IPSOMEDIC & IPSOMEL laboratory, is to develop innovative continuous manufacturing processes of chemical and biological API beneficial to the patient.

It has been developed a full continuous process for the production of Paracetamol (Acetominophen). This new process will be the heart of the IPSOPHENE project whose the plant will be located in Toulouse.

The industrial unit will encompass flexible, safe, green, and mobile modular units on skid. Production capacity can be easily expanded by doing the numbering up – Technology to transfer this unit to other countries. This mode of construction and the implementation of new technologies is the only way to make the relocated production profitable.

The Aubagne Lab fully automated, with a special effort in data analysis, implements innovative reactions , separation modules ; Numbering up techniques reduces the risk associated with the old scaling up methods . Furthermore, Analytical techniques, such Raman, NIR, UV,.. are key technology to control the full process over time.