A New Tool Using Flow Chemistry Techniques for Continuous Crystallization of Pharmaceutical Drugs

In order to answer to the need of patients, it is important to develop innovative solutions to produce new drugs with the right particle size and polymorph in order to control the absorption of the drug by patient.

Then it could be a nice solution to propose a personalized medication, that means to prepare the tablet with the right dose with 3D printing for each patient in order to avoid an overconsumption of drug which can induce second effect for patient.

The new IPSOMEDIC’s lab installed in Aubagne (South in France), proposes the high quality right drug process with the right dose customized for each patient at low cost and safe conditions. The main objective of IPSOMEDIC & IPSOMEL laboratory, is to develop innovative continuous manufacturing processes of chemical and biological API beneficial to the patient.

The industrial unit will encompass flexible, safe, green and mobile modular units on skid . Production capacity can be easily expanded by doing the numbering up – Technology to transfer this unit to other countries. This mode of construction and the implementation of new technologies is the only way to make the relocated production profitable.

The Aubagne Lab fully automated, with a special effort in data analysis, implements innovative reactions , separation modules ; Numbering up techniques
reduces the risk associated with the old scaling up methods.

Furthermore, Analytical techniques, such Raman,.. are key technology to control the particle size of crystallization step and also API concentration in each tablet.