Lessons Learned: Development and Scale-up in Aqueous Systems

The methodology for full scale design of dilute aqueous systems presents a unique set of challenges due to the high latent heat of water. This is particularly challenging when water is the low boiler in the system. This presentation will provide a brief overview of lessons learned while working on the scale-up, heat transfer and equipment design issues in aqueous systems. Topics to be covered include scale-up methodology, aerobic fermentation heat transfer and evaporation of water.