Title | Fast microflow kinetics and acid catalyst deactivation in glucose conversion to 5-hydroxymethylfurfural |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Chen, TYing, Cheng, Z, Desir, P, Saha, B, Vlachos, DG |
Journal | Reaction Chemistry and Engineering |
Volume | 6 |
Pagination | 152–164 |
Date Published | jan |
ISSN | 20589883 |
Keywords | Project 7.6, Renewable Bioproducts |
Abstract | 5-Hydroxymethyl furfural (HMF) is an important platform chemical because it can be upgraded to various drop-in and performance-advantaged products. The cascade reaction of HMF production from glucose over a Lewis acid (CrCl3) and a Brønsted acid (HCl) catalyst in aqueous media is investigated in a microreactor at short residence times and high temperatures. We study the formation of various chromium species using UV-visible spectrophotometry and elucidate the Cr(iii) speciation. The catalyst reactivity increases sharply at short residence times, and then drops at long times. This indicates that the catalyst treatment plays a vital role in getting optimal reactivity, and recording the catalyst history is necessary. We develop a kinetic model to describe the catalyst speciation as well as the Lewis and Brønsted acid-catalyzed reaction kinetics using a hierarchical approach. The model is in good agreement with experiments. We demonstrate the benefits of tandem Lewis-external added Brønsted acid catalysis in processing time, productivity, and catalyst stability. We apply this model to optimize the HMF yield and obtain ∼36% yield at 200 °C in 7 min and report the highest productivity of ∼15% yield per min, demonstrating the opportunity of reaching high productivity at short residence times. |
URL | https://pubs.rsc.org/en/content/articlehtml/2021/re/d0re00391c https://pubs.rsc.org/en/content/articlelanding/2021/re/d0re00391c |
DOI | 10.1039/d0re00391c |
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