Antonella Sistigu | AIChE

Antonella Sistigu

Università Cattolica del Sacro Cuore

I received a first Ph.D. in Cellular and Molecular Biology in 2010 from the University of Rome “Roma Tre” (Rome, Italy), investigating the mechanisms of chemotherapy-induced immune conditioning. I then received a second Ph.D. in Oncology from the University Paris Sud (Paris, France) in 2013 studying the molecular and cellular bases of the immunogenicity of cell death during chemotherapy and radiotherapy. I then worked as a post-doctoral fellow at the Unit of Tumor Immunology and Immunotherapy, Regina Elena National Cancer Institute, (Rome, Italy) studying the mechanisms of cancer stem cell induction upon immunogenic chemotherapy and the immunogenicity of cancer stem cells. I am currently Senior Researcher and Group Leader at the Regina Elena National Cancer Institute (Rome, Italy) and the Department of General Pathology of University of Sacred Hearth of Rome (Rome, Italy) where I am also chair in Tumor Immunology and Immunotherapy. I am coordinating as principal investigator two grants, the “Start-Up AIRC Grant 2016” sponsored by the Fondazione Italiana per la Ricerca sul Cancro and “Giovani Ricercatori,-Ricerca Finalizzata 2013-2014” from Ministero Italiano della Salute. My work focuses on dissecting the molecular mechanisms leading cancer and tumor infiltrating immune cell reprogramming as a mechanism of tumor-host co-evolution under conventional chemotherapy. I am member of the European Academy of Tumor Immunology and of the Review Editor Board of Frontiers in Molecular Immunity and PLOS ONE. I am author of 36 ISI papers including articles in high impact factor journals Science, Nat Med, Trends in Cell Biol, Cancer Res.and Cell Death Differ. “h”index: 19.