Jacob Corn is the Professor of Genome Biology at the ETH Zurich. His research aims to better understand and treat disease through next-generation genome editing technologies. Jacob’s career has bridged academia and industry, working in therapeutic areas that include infectious disease, neurobiology, and oncology. His research takes a multidisciplinary approach, combining cellular biochemistry, functional genomics, computational biology, bioengineering, and biophysics. Jacob’s graduate studies at the University of California, Berkeley with James Berger redefined our understanding of the geometry of DNA replication and was recognized with several honors, including the Nicholas Cozzarelli and Harold Weintraub awards. Jacob’s work as a Jane Coffin Childs postdoctoral fellow at the University of Washington culminated in the world’s first computationally designed de novo protein interaction and a protein-based inhibitor to treat flu. Jacob began his independent research career as a group leader at Genentech, where his lab discovered biological mechanisms for challenging therapeutic targets. Jacob then moved back to academia as the founding Scientific Director of the Innovative Genomics Institute and faculty at UC Berkeley. His lab’s current focus is the development of genome editing, the mechanisms by which cells repair their DNA, and the maintenance of healthy organelles. In his spare time, Jacob enjoys long backpacking trips and rock climbing