GIS Fellow
Genome Institute of Singapore, A*STAR
Dr. Wei Leong Chew is GIS Fellow at the Genome Institute of Singapore, A*STAR. His lab develops technologies for making pinpoint changes in the human genome. His work contributed to the first demonstrations of postnatal disease gene correction and transcriptional activation with CRISPR-Cas9. He identified the immunogenic determinants on AAV-CRISPR-Cas9, providing a first insight into the safety profile of CRISPR therapeutics. He co-directs the Molecular Therapeutics Programme - the first DNA and RNA -targeting therapeutics development center in Southeast Asia. Dr. Chew graduated from Duke University for his B.S., and obtained his Ph.D. with Prof. George Church at Harvard Medical School.