Conference Program
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| Sunday, October 20 | |
| 2:00 PM - 3:00 PM | Badge Pick-up/Check-in |
| 3:00 PM - 3:15 PM | Opening Remarks (Conference Chairs) |
| 3:15 PM - 4:55 PM | Bigger, Stronger, Faster: Synthetic Biology Approaches to Develop more Potent Therapies |
| 3:15 PM - 3:45 PM | Invited Speaker: Crispr's Effect on the Immune Homeostasis: The Culprit and the Savior Samira Kiani, Arizona State University |
| 3:45 PM - 4:15 PM | Invited Speaker: Synthetic Gene Circuits for Cancer Immunotherapy Lior Nissim, The Hebrew University of Jerusalem |
| 4:15 PM - 4:35 PM | DNA-Scaffolded Biomaterials Enable Modular and Tunable Control of Cell-Based Cancer Immunotherapies Xiao Huang, University of California, San Francisco |
| 4:35 PM - 4:55 PM | Growth Kinetics for Cytotoxic T-Lymphocytes to Optimize Expansion in a Centrifugal Bioreactor Anna C. Crowley, Washington State University |
| 5:00 PM - 6:00 PM | Reception & Poster Session |
| Monday, October 21 | |
| 8:00 AM - 9:00 AM | Badge Pick-up/Check-in |
| 9:00 AM - 10:20 AM | Solid Tumors: Increasing Specificity and Overcoming TME Session Chair: Lior Nissim, The Hebrew University of Jerusalem |
| 9:00 AM - 9:30 AM | Invited Speaker: Oncolytic Herpes Simplex Virus Combinations Boosting Immunovirotherapy Samuel Rabkin, Harvard University |
| 9:30 AM - 10:00 AM | Invited Speaker: Next-Generation CAR T Cell Therapies for Treatment of Glioma, Utilizing Sequential Prime-and-Kill Circuits to Achieve Safe and Effective Tumor Targeting Hideho Okada, University of California, San Francisco |
| 10:00 AM - 10:20 AM | Dual Functional Immunostimulatory Polymeric Prodrug Carrier with Pendent Indoximod for Enhanced Cancer Immunochemotherapy Zhuoya Wan, University of Pittsburgh |
| 10:20 AM - 10:50 AM | Break |
| 10:50 AM - 12:20 PM | Beyond Conventional CARs Session Chair: Lior Nissim, The Hebrew University of Jerusalem |
| 10:50 AM - 11:20 AM | Invited Speaker: Human High Affinity T Cell Receptors for Solid and Liquid Tumors Aude Chapuis, Fred Hutchinson Cancer Research Center |
| 11:20 AM - 11:50 AM | Invited Speaker: Promoting Immunotherapy Response in Solid Tumors: A Novel Strategy of Combining CAR T Cell Therapy with PD-1 Blockade Stefan Kiesgen, Memorial Sloan Kettering Cancer Center |
| 12:00 PM - 12:20 PM | A New Class of Universal Chimeric Antigen Receptor Emerges: The Adapter CAR Ronald Dudek, Lentigen Technology, Inc. |
| 12:20 PM - 2:00 PM | Lunch |
| 2:00 PM - 3:00 PM | Gene Editing in Cell Therapy |
| 2:00 PM - 2:30 PM | Invited Speaker: Generation of a Library of WT1-Specific T Cell Receptors (TCR) for TCR Gene Edited T Cell Therapy of Acute Leukemia Eliana Ruggiero, San Raffaele Scientific Institute, Milan |
| 2:30 PM - 3:00 PM | Invited Speaker: Fyodor Urnov, Technology and Translation, Innovative Genomics Institute |
| 3:00 PM - 3:30 PM | Break |
| 3:30 PM - 4:50 PM | Moving Beyond Autologous T cells: Allogeneic and Other Cell Types |
| 3:30 PM - 4:00 PM | Invited Speaker: Beyond T Cell Immune Checkpoint Inhibitors for Cancer Therapy Shiladitya Sengupta, Massachusetts Institute of Technology |
| 4:00 PM - 4:30 PM | Invited Speaker: Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cells for Cancer Immunotherapy Lili Yang, University of California, Los Angeles |
| 4:30 PM - 4:50 PM | CAR Macrophages for the Treatment of Metastatic Solid Tumors Nicholas R. Anderson, Carisma Therapeutics |
| Tuesday, October 22 | |
| 8:00 AM - 9:00 AM | Registration |
| 9:00 AM - 10:50 AM | Update from the frontline: CARs in the clinic |
| 9:00 AM - 9:30 AM | Invited Speaker: CAR T Cell Trogocytosis and Cooperative Killing Regulate Tumor Antigen Escape Mohamad Hamieh, Memorial Sloan Kettering Cancer Center |
| 9:30 AM - 10:00 AM | Invited Speaker: CAR-T Antigen Evasion: The Emerging Role for Multi-Targeted CAR Therapy David Miklos, Stanford University |
| 10:00 AM - 10:30 AM | Invited Speaker: Saul Priceman, City of Hope |
| 10:30 AM - 10:50 AM | CAR T-Cell Populations Associated with Complete Response or Progressive Disease in Adult Lymphoma Patients Treated with Axi-Cel Zinaida Good, Stanford University |
| 10:50 AM - 11:20 AM | Break |
| 11:20 AM - 12:00 PM | Cell Therapy Applications Beyond Oncology |
| 11:20 AM - 11:50 AM | Invited Speaker: Targeting CAR T Cells to Lymphoid Follicles to Cure HIV Pamela Skinner, University of Minnesota |
| 11:50 AM - 12:20 PM | Invited Speaker: Designing Next-Generation Engineered Regulatory T Cell Therapies Leonardo Ferreira, University of California, San Francisco |
| 12:20 PM - 12:40 PM | Engineered (LV)FOXP3 Treg-like Cells Protect from Lymphoproliferation While Preserving Immune Responses in Humanized-Mice Models Yohei Sato, Stanford University |
| 12:40 PM - 2:00 PM | Lunch |