Technical Program
*Please note this schedule is subject to change. Check back frequently for updates. Last updated 12.8.18
...
*Please note this schedule is subject to change. Check back frequently for updates. Last updated 12.8.18
Monday, December 10
| 7:30 AM - 12:00 PM | Registration |
| 8:00 AM - 8:45 AM | Morning Coffee & quick start breakfast |
| 8:45 AM - 9:00 AM | Welcome |
| 9:00 AM - 9:45 AM | Keynote Speaker - Fyodor Urnov, Genomics Institute/Altius Institute |
| 9:45 AM - 12:00 PM | Session 1: CRISPR-Cas Biology |
| Chair: Chase Beisel, Helmholtz Institute | |
| 9:45 AM - 10:15 AM | Molecular Technologies for Transcriptome Engineering, Invited Speaker: Patrick Hsu, Salk Institute |
| 10:15 AM - 10:45 AM | Coffee Break |
| 10:45 AM - 11:15 AM | Programmable RNA Recognition and Cleavage By N. Meningitidis CRISPR-Cas9, Invited Speaker: Yan Zhang, University of Michigan |
| 11:15 AM - 11:30 AM | Discovery of Widespread Type I and Type V CRISPR-Cas Inhibitors, Nicole Marino, University of California, San Francisco |
| 11:30 AM - 11:45 AM | Molecular Basis of Off-Target Effects in CRISPR-Cas9, Giulia Palermo, University of California, Riverside |
| 11:45 AM - 12:00 PM | Using Artificial Intelligence Algorithms to Improve CRISPR-Cas9 Specificity, Jin Liu, University of North Texas Health Science Center |
| 12:00 PM - 1:30 PM | Lunch |
| 1:30 PM - 3:00 PM | Session 2: Genome editing and DNA repair |
| Chair: Alexis Komor, University of California, San Diego | |
| 1:30 PM - 2:00 PM | Beyond Double Stranded DNA Breaks: Using Uracil and Inosine As Genome Editing Intermediates, Invited Speaker: Alexis Komor, University of California, San Diego |
| 2:00 PM - 2:30 PM | Genome Editing: From Fundamental DNA Repair Mechanisms to Cutting-Edge Applications, Invited Speaker: Yinan Kan, eGenesis |
| 2:30 PM - 2:45 PM | Isolation of Genomic DXR Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin, Gur Pines, University of Colorado Boulder |
| 2:45 PM - 3:00 PM | CRISPR-Based Editing Reveals Edge-Specific Effects in Biological Networks, Chance Nowak, The University of Texas at Dallas |
| 3:00 PM - 3:30 PM | Coffee Break |
| 3:30 PM - 5:45 PM | Session 3: Beyond editing: Novel applications |
| Chair: Harris Wang, Columbia University | |
| 3:30 PM - 4:00 PM | Biological Recording of Cellular Events on CRISPR Tape, Invited Speaker: Harris Wang, Columbia University |
| 4:00 PM - 4:15 PM | CRISPR Adaptation as a Versatile Molecular Recording Platform for Fundamental Research and Biotechnology, Seth Shipman, University of California, San Francisco/Gladstone Institutes |
| 4:15 PM - 4:30 PM | High-Throughput Cas9-Mediated Genome Engineering for Eukaryotic Genome Interrogation, Xiaoge Guo, Harvard Medical School |
| 4:30 PM - 4:45 PM | Engineering Predictable, Tunable Gene Repression Based on Type I-E CRISPR Interference, Katia Tarasava, University of Colorado Boulder |
| 4:45 PM - 5:00 PM | Developmental Barcoding and Lineage Tracing in Mice Using Homing CRISPR, Reza Kalhor, Harvard Medical School |
| 5:00 PM - 5:15 PM | Mammalian Cells That Record Their Own History, Theresa Loveless, University of California, Irvine |
| 5:15 PM - 5:45 PM | Invited Speaker: Megan Palmer, Stanford University |
Tuesday, December 11
| 8:15 AM - 12:00 PM | Registration |
| 8:15 AM - 9:15 AM | Morning Coffee |
| 9:15 AM - 11:45 AM | Session 4: Clinical applications & CRISPR-based gene drives |
| Chair: Omar Akbari, University of California, San Diego | |
| 9:15 AM - 9:45 AM | Using CRISPR to Combat Human Disease Vectors, Invited Speaker: Omar Akbari, University of California, San Diego |
| 9:45 AM - 10:00 AM | Progress Towards Developing CRISPR-Based Genetic Pest Management Strategies for Spotted Wing Drosophila (SWD), Anna Buchman, University of California, San Diego |
| 10:00 AM - 10:30 AM | Coffee Break |
| 10:30 AM - 11:00 AM | Highly Efficient Single and Multi-Gene Knockout with CRISPR-Cpf1 in T Cells for the Development of Improved Cell Therapies, Invited Speaker: John Zuris, Editas Medicine |
| 11:00 AM - 11:30 AM | Therapeutic Strategies Via Genome Engineering: New Approaches and New Challenges, Invited Speaker: Prashant Mali, University of California, San Diego |
| 11:30 AM - 11:45 AM | A Novel Automation Platform for Generating CRISPR-Engineered Cells at Scale, Kevin Holden, Synthego |
| 11:45 AM - 12:00 PM | Creating Hereditary Persistence of Fetal Hemoglobin (HPFH) with CRISPR/Cas9 To Treat Beta-Thalassemia (Beta-Thal) and Sickle Cell Disease (SCD), TJ Cradick, CRISPR Therapeutics |
| 12:00 PM - 1:45 PM | Lunch |
| 1:45 PM - 2:00 PM | Session 5: Social, ethical, and economic implications of CRISPR-based technologies |
| 1:45 PM - 2:00 PM | Re-Framing Public Engagement to Promote Public Trust in CRISPR Technologies, Christian Ross, Arizona State University |
| 2:00 PM - 3:00 PM | Session 6: Delivery and Specificity of CRISPR-based tools (I) |
| 2:00 PM - 2:30 PM | A Growth-Based Screen Reveals Non-Canonical Pams for the Streptococcus Pyogenes Cas9, Invited Speaker: Chase Beisel, Helmholtz Institute |
| 2:30 PM - 2:45 PM | Developing New Tools and Technologies for Precision Genome Editing, Peter Cameron, Caribou Biosciences |
| 2:45 PM - 3:00 PM | Poster Setup |
| 3:00 PM - 4:30 PM | Poster Session/Reception |
Wednesday, December 12
| 8:15 AM - 12:00 PM | Registration |
| 8:15 AM - 9:00 AM | Morning Coffee |
| 9:00 AM - 12:00 PM | Session 7: Delivery and Specificity of CRISPR-based tools (II) |
| Chairs: Mo Ebrahimkhani, Arizona State University & Shengdar Tsai, St. Jude Children's Research Hospital | |
| 9:00 AM - 9:30 AM | Engineering Gene Regulatory Network for Synthetic Morphogenesis of Multicellular Mammalian Tissues, Invited Speaker: Mo Ebrahimkhani, Arizona State University |
| 9:30 AM - 10:00 AM | Illuminating the Genome-wide Activity of CRISPR-Cas Nucleases for Therapeutics, Invited Speaker: Shengdar Tsai, St. Jude Children's Research Hospital |
| 10:00 AM - 10:30 AM | Safer AAV-CRISPR-Cas Therapeutics, Invited Speaker: Wei Leong Chew, Genome Institute of Singapore |
| 10:30 AM - 11:00 AM | Coffee Break |
| 11:00 AM - 11:15 AM | Target Enrichment and High-Resolution NGS Analysis of on- and Off-Target CRISPR/Cas9 Editing Events, Ashley Jacobi, IDT |
| 11:15 AM - 11:45 AM | Genome Editing for Duchenne Muscular Dystrophy, Invited Speaker: Charles Gersbach, Duke University |
| 11:45 AM - 12:00 PM | Closing Remarks |
