Rest Stability Control By EZH2 Underlies Chromatin Remodeler Switching during Microrna-Mediated Neuronal Reprogramming of Human Adult Fibroblasts
International Conference on Epigenetics and Bioengineering
2017
International Conference on Epigenetics and Bioengineering
Poster Session
Poster Session
Wednesday, December 13, 2017 - 4:45pm to 6:30pm
1. Victor, M.B. et al. Generation of human striatal neurons by microRNA-dependent direct conversion of fibroblasts. Neuron 84, 311-323 (2014).
2. Richner, M., Victor, M.B., Liu, Y., Abernathy, D. & Yoo, A.S. MicroRNA-based conversion of human fibroblasts into striatal medium spiny neurons. Nat Protoc 10, 1543-1555 (2015).
3. Huh, C.J. et al. Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts. Elife 5 (2016).
4. Yoo, A.S. et al. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 476, 228-231 (2011).
5. Abernathy., D.G. et al. MicroRNAs Induce a Permissive Chromatin Environment That Enables Neuronal Subtype-specific Reprogramming of Adult Human Fibroblasts. Cell Stem Cell (in press) (2017).
6. Chong, J.A. et al. REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80, 949-957 (1995).
7. Schoenherr, C.J. & Anderson, D.J. The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 267, 1360-1363 (1995).
8. Cao, R. et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298, 1039-1043 (2002).
9. Margueron, R. & Reinberg, D. The Polycomb complex PRC2 and its mark in life. Nature 469, 343-349 (2011).
10. Yoo, A.S., Staahl, B.T., Chen, L. & Crabtree, G.R. MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature 460, 642-646 (2009).
11. Yoo, A.S. & Crabtree, G.R. ATP-dependent chromatin remodeling in neural development. Curr Opin Neurobiol 19, 120-126 (2009).
12. Yoo, M. et al. BAF53b, a Neuron-Specific Nucleosome Remodeling Factor, Is Induced after Learning and Facilitates Long-Term Memory Consolidation. J Neurosci 37, 3686-3697 (2017).