Technical Program
Thursday, September 12
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Thursday, September 12
| 7:30 AM - 12:00 PM | Registration | ||
| 9:00 AM - 9:45 AM | Keynote Speaker | Luciano Di Croce | Epigenetic mechanisms governing cell differentiation and cancer processes |
| 9:45 AM - 12:00 PM | Session Ia: Writing Epigenetic Modifications (Chair: M. G. Rots) | ||
| 9:45 AM - 10:15 AM | Invited Speaker | Nate Hathaway | Chemically Activating Chromatin |
| 10:15 AM - 10:30 AM | Selected Speaker | Isaac Hilton | Deciphering the Histone Acetyl Code in Human Cells with dCas9-Based Epigenome Editing |
| 10:30 AM - 11:00 AM | Coffee Break | ||
| 11:00 AM - 11:15 AM | Selected Speaker | Nicolas Marx | CRISPR-Based Targeted Epigenetic Editing Enables Glyco-Engineering in Chinese Hamster Ovary (CHO) Cells |
| 11:15 AM -12:00 PM | Keynote Speaker | Charles Gersbach | Epigenome Editing to Program Cell Fate Decisions |
| 12:00 PM - 2:00 PM | Lunch Break | ||
| 2:00 PM - 5:00 PM | Session Ib: Writing Epigenetic Modifications (Chair: TBD) | ||
| 2:00 PM -2:30 PM | Invited Speaker | Guoliang Xu | DNA Methylation and Oxidation in Developmental Control |
| 2:30PM -3:00 PM | Invited Speaker | Albert Jeltsch | Setting of DNA methylation patterns - you see the environment |
| 3:00 PM - 3:30 PM | Coffee Break | ||
| 3:30 PM - 3:45 PM | Selected Speaker | Alexandre Segelle | Epigenome Editing of Alternatively Spliced Exons Relevant for the EMT Is Sufficient to Change Splicing Outcome |
| 3:45 PM -4:00 PM | Selected Speaker | Tessa Swain | Highly Effective Epigenome Editing and Gene Regulation By the Customizable dCas9-Sssavi Combinatorial Recruitment Platform |
| 4:00 PM - 5:30 PM | Poster Session | ||
Friday, September 13
| 7:30 AM - 12:00 PM | Registration | ||
| 9:00 AM - 12:00 PM | Session II: Sensing and detection of epigenetic modifications (Chair: A. Jeltsch) | ||
| 9:00 AM - 9:30 AM | Invited Speaker | Philipp Voigt | Nucleosomal Asymmetry Shapes Histone Mark Binding at Bivalent Domains |
| 9:30 AM - 10:00 AM | Invited Speaker | Marianne G Rots | mtDNA methylation: is it or is it not (what is the true question?)? |
| 10:00 AM -10:15 AM | Selected Speaker | Yuchen Gao | Synthetic Heterochromatin Domain Formation Via CRISPR/dCas9 |
| 10:15 AM -10:30 AM | Selected Speaker | Hiroshi Kimura | Modification-Specific Intracellular Antibodies for Monitoring Histone Modification and Transcription In Vivo |
| 10:30 AM - 11:00 AM | Coffee Break | ||
| 11:00 AM -11:15 AM | Selected Speaker | Edita Kriukiene | Precise DNA Epigenome Profiling: High-Resolution Economical Approaches for Detection of Genomic Cytosine Modifications |
| 11:15 AM -11:30 AM | Selected Speaker | Philipp Rathert | Dynamics and Wiring of Chromatin Regulators |
| 11:30 AM -11:45 AM | Selected Speaker | Rodrigo Villasenor | Engineered Chromatin Readers Reveal the Genome-Wide Proteome Composition at Key Chromatin States in Living Cells |
| 11:45 AM -12:00 AM | Selected Speaker | Gergana Velikova | Development of a Computational Tool for the Analysis of Bisulfite-Free DNA Sequencing Data |
| 12:00 PM - 2:00 PM | Lunch Break | ||
| 2:00 PM - 4:30 PM | Session III: Single cell Epigenetics (Chair: TBD) | ||
| 2:00 PM - 2:30 PM | Invited Speaker | Albert Keung | Human cerebral organoids model disease-relevant gene expression dynamics |
| 2:30 PM - 3:00 PM | Invited Speaker | Carolina Florian | Aging alters the epigenetic asymmetry of HSC division |
| 3:00 PM - 3:30 PM | Coffee Break | ||
| 3:30 PM - 4:00 PM | Invited Speaker | Pernette Verschure | Dynamic epigenetic regulation: Single cells can make a difference |
| 4:00 PM - 4:15 PM | Selected Speaker | H. Courtney Hodges | Regulation of Chromatin State in 3D Tissues |
| 4:15 PM - 4:30 PM | Selected Speaker | Sai Ma | Integrative Single-Cell Chromatin and Transcriptome Profiling Uncovers Cell-Type Specific Regulatory Interactions |
Saturday, September 14
| 7:30 AM - 12:00 PM | Registration | ||
| 9:00 AM - 9:45 AM | Keynote Speaker | Dave Segal | Changing Your Mind: Targeted Epigenetic Editing in the Brain |
| 9:45 AM - 10:30 PM | Session IV: Epigenetic control of Development (Chair: TBD) | ||
| 9:45 AM - 10:15 AM | Invited Speaker | Michael Zeisberg | Epigenetic control of fibroblast activation |
| 10:15 AM - 10:30 AM | Selected Speaker | Giovanni Carosso | Precocious Neuronal Differentiation and Disrupted Oxygen Responses from KMT2D Loss in Kabuki Syndrome |
| 10:30 AM - 11:00 AM | Coffee Break | ||
| 11:00 AM - 12:00 PM | Session V: Cancer Epigenetics (Chair: TBD) | ||
| 11:00 AM - 11:30 AM | Invited Speaker | Pilar Blancafort | Epigenetic engineering in the cancer microenvironment |
| 11:30 PM - 12:00 PM | Invited Speaker | Lucia Altucci | Targeting Cancer Epigenome: strategies for prevention and treatment |
| 12:00 PM - 12:45 PM | Keynote Speaker | Paola Arimodo | Chemical Targeting of DNA and histone methylation to reprogram cells in human diseases: challenges and future perspectives |
| 12:45 PM - 1:00 PM | Closing Remarks | ||