Technical Program | AIChE

Technical Program

Technical Program ...

Technical Program

(this program is subject to change)

Confex Program with Abstracts

Day 1 - 3 October 2024

Start Time End Time  
9:00 AM 10:00 AM Registration (open all day) 
9:45 AM 10:00 AM

Conference Introduction
Conference Chairs:
Nate Hathaway - University of North Carolina at Chapel Hill
Karmella Haynes - Emory University
Pernette Verschure - University of Amsterdam

10:00 AM

10:45 AM

The EMBO Keynote Lecture                            
Wendy Bickmore - University of Edinburgh                                 

10:45 AM 11:15 PM Coffee Break
11:15 PM 12:35 PM Session 1 - Perturbing Chromatin and Epigenetic Editing
Session Chair: Nate Hathaway - University of North Carolina at Chapel Hill
11:15 AM 11:40 AM Specificity of DNMTs in Nature and Engineering
Albert Jeltsch - University of Stuttgart
11:40 AM 12:05 AM Dynamic Epigenetic Regulation and Transcription Bursting in Single Cells
Pernette Verschure - University of Amsterdam
12:05 PM 12:20 PM Direct Reprogramming of Primary Human Astrocytes to Functional
Neurons with CRISPR-Based Epigenome Editing

Samuel Reisman - Duke University
12:20 PM 12:35 PM Tailoring a CRISPR/Cas-Based Epigenome Editor for Programmable
Chromatin Acylation and Decreased Cytotoxicity

Jacob Goell - Rice University
12:35 PM 2:00 PM Lunch
Lunch with a Legend - Wendy Bickmore - University of Edinburgh
2:00 PM 2:40 PM

Session 2 - Poster Presenter Lightning Talks
Session Chair: Aibhlin Moye-Linehan - AIChE

2:40 PM 4:30 PM Poster & Sponsor Exhibit Reception with Refreshments
 

Day 2 - 4 October 2024

Start Time End Time  
9:00 AM 10:00 AM Registration (open all day) 
9:45 AM 10:00 AM

Morning Introduction
Conference Chairs:
Nate Hathaway - University of North Carolina at Chapel Hill
Karmella Haynes - Emory University
Pernette Verschure - University of Amsterdam

10:00 AM

10:45 AM

Keynote Presentation
Lei Stanley Qi - Stanford University

10:45 AM 11:15 AM Coffee Break
11:15 AM 12:35 PM Session 3 - Emerging Technologies in Epigenetic and Chromatin Research I
Session Chair: Albert Jeltsch - University of Stuttgart
11:15 AM 11:40 AM Dissecting mRNA decoding using long-term tracking of single ribosomes
Marvin Tanenbaum - Hubrecht Institute
11:40 AM 12:05 PM Programming the Epigenome to Dissect Chromatin Function
Jamie Hackett - European Molecular Biology Laboratory
12:05 PM 12:20 PM ATAC-Mass Enables Holistic Chromatin Accessibility Analysis By Sequencing,
Mass Cytometry, and High-Resolution Imaging

Kim Kira Witetzek - Academia Sinica
12:20 PM 12:35 PM Dynamic In Vivo mapping of the Methylproteome Using a Chemoenzymatic Approach
Jennifer Spangle - Emory University
12:35 PM 2:00 PM Lunch & Round Table Discussion
Responsible Innovation in Epigenetic Engineering
Michelle Habets - Rathenau Institute
2:00 PM 3:20 PM Session 4 - Sensing Epigenetic Modifications
Session Chair: Karmella Haynes - Emory University
2:00 PM 2:25 PM Location, location, location: Probing the functional landscape of a genomic locus
Bas van Steensel - Netherlands Cancer Institute
2:25 PM 2:50 PM

Probing chromatin-protein interactions during dynamic regulatory processes
Tuncay Baubec - Utrecht University

2:50 PM 3:05 PM Modular Dual-Color Bimolecular Anchor Detector Sensors for Locus-Specific
Readout of Epigenome Modifications in Single Cells

Anja R. Koehler - University of Stuttgart
3:05 PM 3:20 PM

Mapping Post-Translational Modifications with Tandem Epigenetic Reader
Domains Provides New Insights on the Histone Code

Matthew MeinersEpiCypher

3:20 PM 3:35 PM Deciphering the Role of Allele-Specific DNA Methylation in Autosomal Monoallelic
Expression with Long-Read Sequencing

Alexander Gimelbrant - Altius Institute for Biomedical Sciences
3:35 PM

4:05 PM

Afternoon Break

4:05 PM

5:00 PM Session 5 - Emerging Technologies in Epigenetic and Chromatin Research II
Session Chair: Jennifer Spangle - Emory University

4:05 PM

4:30 PM Development of compact transcriptional effectors using high-throughput
measurements in diverse contexts

Lacramioara Bintu - Stanford University
4:30 PM 4:45 PM A Combinatorial Domain Screening Platform Reveals Epigenetic Effector
Interactions for Transcriptional Perturbation

Michael Herschl - UC Berkeley
4:45 PM 5:00 PM Engineering Metabolic Cascades for Selective Chemical
Tracking of Epigenetic Signaling in Live Cells

Saulius Klimašauskas - Vilnius University
 

Day 3 - 5 October 2024

Start Time               End Time  
Start Time End Time  
9:00 AM 10:00 AM Registration (open all day) 
9:45 AM 10:00 AM

Morning Introduction
Conference Chairs:
Nate Hathaway - University of North Carolina at Chapel Hill
Karmella Haynes - Emory University
Pernette Verschure - University of Amsterdam

10:00 AM

10:45 AM

Keynote Presentation
Angelo Lombardo - Vita-Salute San Raffaele University
Session Chair: Marianne Rots - University Medical Center Groningen

10:45 AM 11:15 PM Coffee Break
11:15 PM 12:35 PM Session 6 - Computational Epigenetics
Session Chair: Isaac Hilton - Rice University
11:15 AM 11:40 AM

Constructing gene regulatory networks using epigenetic data 
Kimberly Glass - Harvard Medical School 

11:40 AM 11:55 AM The Catalytic Machinery of Protein Lysine Methyltransferases - Powerful Synergistic
Research of Molecular Dynamics Simulation and Biochemistry

Philipp Schnee - University of Stuttgart
11:55 PM 12:10 PM Analog Epigenetic Cell Memory By Graded DNA Methylation
Domitilla Del Vecchio - Massachusetts Institute of Technology
12:10 PM 1:30 PM Lunch
1:30 PM 2:50 PM Session 7 - Directions in Clinical Epigenetic Engineering
Session Chair: Karmella Haynes - Emory University
1:30 PM 1:55 PM Physiological roles of aberrant DNA methylation in vitro and in vivo
Gabriella Ficz - Barts Cancer Institute, Queen Mary University
1:55 PM 2:20 PM Do some loci have a propensity to retain ectopic methylation?
Henriette O'Geen - University of California-Davis
2:20 PM 2:35 PM Multi-Level Proteomics Reveals Epigenetic Signatures in
BCG-Mediated Macrophage Activation

Ivana Parker - University of Florida
2:35 PM 2:50 PM Systemic Comparison of dCas9-Based DNA Methylation Editing
Systems for Specificity and Stability

Majid Pahlevan Kakhki - Karolinska Institutet
2:50 PM 4:00PM Closing Remarks and Networking Time with Refreshments