Technical Program
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| Day 1 | ||
| Start Time | End Time | |
| 8:00 AM | 4:00 PM | Registration |
| 9:00 AM | 9:15 AM | Welcome Remarks by Chairs Xiaojing Gao, Stanford University and Tara Deans, University of Utah |
| 9:15 AM | 10:00 AM | Keynote Speaker: From Precise Microbial Genomics to Precision Medicine, Ami Bhatt, Stanford University |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 12:00 PM | Session 1: The Evolution of mSBW Chairs: Xiaojing Gao and Ron Weiss |
| 10:30 AM | 11:00 AM | Invited Speaker: Liz Wayne, Carnegie Mellon |
| 11:00 AM | 11:30 AM | Invited Speaker: Caleb Bashor, Rice University |
| 11:30 AM | 11:45 AM | Selected Abstract: Programmable Protein Delivery with a Bacterial Contractile Injection System, Joseph Kreitz, Broad Institute of MIT and Harvard |
| 11:45 AM | 12:00 PM | Selected Abstract: Integrating Synthetic Biology and Niche Engineering to Produce TCR- and CAR-T Cells from Pluripotent Stem Cells, Ross D. Jones, University of British Columbia |
| 12:00 PM | 1:15 PM | Lunch |
| 1:15 PM | 2:00 PM | Keynote Speaker: From Mapping To Modeling The Architecture Of Human Cells, Emma Lundberg, Stanford University |
| 2:00 PM | 3:30 PM | Session 2: Foundational Technologies Chairs: Lacra Bintu and Mo Khalil |
| 2:00 PM | 2:30 PM | Invited Speaker: Navigating the Evolutionary Landscape: A Real-time Platform for Continuous Evolution of Biomolecules, Emma Chory, Duke University |
| 2:30 PM | 3:00 PM | Invited Speaker: Resource-aware construct design in mammalian cells, Francesca Ceroni, Imperial College London |
| 3:00 PM | 3:15 PM | Selected Abstract: Targeted Epigenetic Perturbations Reveal a Quantitative Link between Chromatin Compaction and Epigenetic Memory, Taihei Fujimori, Stanford University |
| 3:15 PM | 3:30 PM | Selected Abstract: Harnessing Protein-Protein Interactions for Programmable Control of Protein Secretion in Mammalian Cells, Alexander Vlahos, Stanford University |
| 3:30 PM | 3:40 PM | Funding Landscape and Opportunities at the NIH, Nichole Daringer, NIH/NIBIB |
| 3:40 PM | 5:10 PM | Poster Session 1 with Afternoon Coffee Break |
| 5:10 PM | 6:40 PM | Session 3: Reporters and Recorders Chairs: Leonardo Morsut and Tara Deans |
| 5:10 PM | 5:40 PM | Invited Speaker: John Ngo, Boston University |
| 5:40 PM | 6:10 PM | Invited Speaker: Continuous Recording Of Cell History Into DNA, Theresa Loveless, Rice University |
| 6:10 PM | 6:25 PM | Selected Abstract: Modular and Tunable Gene Expression Sensing and Response without Modifications to Endogenous Gene Coding Sequences, Fabio Caliendo, Massachusetts Institute of Technology |
| 6:25 PM | 6:40 PM | Selected Abstract: Development of a Post-Transcriptional Modular Synthetic Receptor Platform for Therapeutic Applications and Research, Xiaowei Zhang, Stanford University |
| Day 2 | ||
| Start Time | End Time | |
| 8:00 AM | 4:00 PM | Registration |
| 9:00 AM | 9:45 AM | Keynote Speaker: Chronogenetic gene circuits in synthetic biology: It’s about time, Farsh Guliak, Washington University |
| 9:45 AM | 10:15 AM | Morning Coffee Break |
| 10:15 AM | 11:45 AM | Session 4: Circuits and Dynamics Chairs: Diego di Bernardo and Tara Deans |
| 10:15 AM | 10:45 AM | Invited Speaker: A Synthetic Protein-Level Neural Network in Mammalian Cells, Zibo Chen, Westlake University |
| 10:45 AM | 11:15 AM | Invited Speaker: Seeing and controlling dynamic cell biology with programmable reaction-diffusion circuits, Scott Coyle, University of Wisconsin-Madison |
| 11:15 AM | 11:30 AM | Selected Abstract:Inteins in the Loop: A Framework for Engineering Advanced Biomolecular Controllers for Robust Perfect Adaptation, Stanislav Anastassov, ETH Zürich |
| 11:30 AM | 11:45 AM | Selected Abstract: SNAP Circuits: A Highly-Modular Framework for Protein-Responsive RNA-Based Controllers, Kei Takahashi, Massachusetts Institute of Technology |
| 11:45 AM | 12:45 PM | Lunch |
| 12:45 PM | 1:30 PM | Keynote Speaker: Engineering Pluripotent Stem Cell Derived T-Cell Development, Peter Zandstra, University of British Colombia |
| 1:30 PM | 3:00 PM | Session 5: Regenerative Medicine and Organoids + Translational Chairs: Leonardo Morsut and Katie Galloway |
| 1:30 PM | 2:00 PM | Invited Speaker: Anti-Hypertrophic and Anti-Inflammatory Effects of Autonomous RUNX2 Suppression in Engineered Cartilage, Rhima Coleman, University of Michigan |
| 2:00 PM | 2:30 PM | Invited Speaker: Targeted Degradation of Membrane Proteins: A Heterobispecific Antibody Approach, Xin Zhou, Harvard Medical School |
| 2:30 PM | 2:45 PM | Selected Abstract: Genetically Engineered Human Pluripotent Stem Cells Utilizing Multi-Step Automated Differentiation Networks for Development of Three-Dimensional Liver Organoids, Deepak Mishra, MIT |
| 2:45 PM | 3:00 PM | Selected Abstract: Design of Multicellular Synthetic Gene Circuits for Spatial Fate Propagation and Their Use for Programming the Elongation of Spheroids Made of Mammalian Cells, Josquin Courte, USC Keck School of Medicine |
| 3:00 PM | 4:30 PM | Poster Session 2 with Afternoon Coffee Break |
| 4:30 PM | 6:00 PM | Session 6: Immunoengineering Chairs: Velia Siciliano and Rogelio Hernandez-Lopez |
| 4:30 PM | 5:00 PM | Invited Speaker: Decoding the language of signaling domains to control cell function, Kyle Daniels, Stanford University |
| 5:00 PM | 5:30 PM | Invited Speaker: Elucidating and manipulating immune biology using de novo engineered cytokine mimetics, Jamie Spangler, John Hopkins |
| 5:30 PM | 5:45 PM | Selected Abstract:Using Deep Learning to Generate Synthetic Proteins with Reduced Immunogenicity, Michael Garton, University of Toronto |
| 5:45 PM | 6:00 PM | Selected Abstract: Systematic Conversion of Natural Human Receptors into Modular Synthetic Biosensors, Amparo Cosio, Northwestern University |
| 6:00 PM | 6:15 PM | Closing Remarks by Chairs: Xiaojing Gao, Stanford University and Tara Deans, University of Utah |
