Technical Program
Technical Program for the 5th ICME
Please see below for the Technical Program. To view speaker abstracts, please click here.
| Start Time | End Time | |
| December 9, 2022 | All Eastern US Time | |
| 8:00 AM | 4:00 PM | Registration & Check In |
| 8:30 AM | 9:00 AM | Breakfast + Morning Coffee |
| Day 1 | ||
| 9:00 AM | 10:00 AM | Opening Statements & Keynote |
| 9:00 AM | 9:10 AM | Day 1 Introduction by Chairs: Megan McClean, University of Wisconsin-Madison & Mark Charbonneau, Solarea Bio |
| 9:10 AM | 10:00 AM | KEYNOTE: Domesticating and Engineering Microbiomes across Diverse Environments, Harris Wang, Columbia University |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 12:25 PM | Tools, Standards and Modeling (Development and Use of Microbiomes) Chair: Megan McClean |
| 10:30 AM | 10:35 AM | Session Introduction: Megan McClean, University of Wisconsin-Madison |
| 10:35 AM | 11:00 AM | Genetically stable CRISPR-based tools for engineering microbiota, Tae Seok Moon, Washington University in St. Louis |
| 11:00 AM | 11:25 AM | Using gnotobiotic mouse models to understand factors influencing microbiome modulation, Amanda Ramer-Tait, University of Nebraska |
| 11:25 AM | 11:50 AM | Synthetic communities and gnotobiotic mouse models to understand functions of the intestinal microbiome, Barbel Stecher, Ludwig-Maximilians University Munich |
| 11:50 AM | 12:10 PM | Radical Genetic Code Engineering to Block Viral Infections and Horizontal Gene Transfer, Akos Nyerges, Harvard Medical School |
| 12:10 PM | 12:15 PM | Lightning Talk: A Chemical Reaction Similarity Based Prediction Algorithm to Identify the Multiple Taxa Required to Catalyze an Entire Metabolic Pathway of Dietary Flavonoids, Ebru Ece Gulsan, Tufts University |
| 12:15 PM | 12:20 PM | Lightning Talk: Studying Personalized Interventions with Metagenome-Scale Metabolic Models of the Human Gut Microbiota, Christian Diener, Institute for Systems Biology |
| 12:20 PM | 12:25 PM | Lightning Talk: Targeting Oncogenic Pathogens in Colon Cancer, Kimberley Owen, University College London |
| 12:25 PM | 1:25 PM | Lunch Workshop by Cerillo: A Novel Co-Culture Method: a Case Study for Improved Bacterial Interaction Studies, Jessica Lee, Cerillo |
| 1:25 PM | 3:00 PM | Therapeutics (Clinical Applications and Drug Development) Part 1 Chair: Lauren Popov |
| 1:25 PM | 1:30 PM | Session Introduction: Lauren Popov, Novome Biotechnologies |
| 1:30 PM | 1:55 PM | Development of SBD111 as a Medical Food for the Dietary Management of Post-Menopausal Osteoporosis, Mark Charbonneau, Solarea Bio |
| 1:55 PM | 2:15 PM | Gut Commensals Associated with Inflammatory Bowel Disease Degrade Components of the Extracellular Matrix, Ana Porras, University of Florida |
| 2:15 PM | 2:40 PM | VE303, a defined consortia for prevention of Clostridium difficile infection, Greg Medlock, Vedanta |
| 2:40 PM | 3:00 PM | Engineering Probiotic Strains to Secrete Therapeutic Molecules to Treat Inflammatory Bowel Disease, Kelly Storek, Genentech Inc. |
| 3:00 PM | 3:30 PM | Afternoon Coffee Break |
| 3:30 PM | 4:15 PM | Panel Discussion: Opportunities and Challenges for Microbiome Therapeutics Moderator: Mark Charbonneau Panel: Greg Medlock, Lauren Popov, Kelly Storek |
| 4:15 PM | 5:15 PM | Poster Session A |
| December 10, 2022 | ||
| 9:00 AM | 4:00 PM | Registration & Check In |
| 9:30 AM | 10:00 AM | Breakfast + Morning Coffee |
| Day 2 | ||
| 10:00 AM | 10:30 AM | Introduction & Keynote |
| 10:00 AM | 10:05 AM | Day 2 Introduction by Chair: Megan McClean, University of Wisconsin-Madison |
| 10:05 AM | 10:30 AM | KEYNOTE: Greg Medlock, Vedanta |
| 10:30 AM | 11:00 AM | Morning Coffee Break |
| 11:00 AM | 2:30 PM | Engineering Microbes and Microbial Communities Chairs: Megan McClean |
| 11:00 AM | 11:05 AM | Session Introduction: Megan McClean, University of Wisconsin-Madison |
| 11:05 AM | 11:30 AM | Towards precision evolution of single microbes and communities, Kiran Patil, University of Cambridge |
| 11:30 AM | 11:55 AM | Predicting and controlling gene transfer in microbial communities, Lingchong You, Duke |
| 11:55 AM | 12:20 PM | Genetic Manipulation of Nonmodel Gut Microbes Enables Single-Gene Interrogation in a Complex Microbiome, Chunjun Guo, Weill Cornell Medicine |
| 12:20 PM | 1:20 PM | Lunch |
| 1:20 PM | 1:45 PM | Engineering defined bacterial consortia for therapeutics based on trophic interactions, Gabriel Leventhal, PharmaBiome |
| 1:45 PM | 2:10 PM | Eco-evolutionary dynamics and metabolic mechanisms in microbial systems, William Harcombe, University of Minnesota |
| 2:10 PM | 2:30 PM | Targeted DNA Editing Within Microbial Communities, Benjamin E. Rubin, University of California, Berkeley & Brady Cress, University of California |
| 2:30 PM | 4:50 PM | Engineering Microbes for Sustainable Planet And Industrial Applications Session Chair: Shannon Sirk |
| 2:30 PM | 2:35 PM | Session Introduction: Shannon Sirk, University of Illinois Urbana-Champaign |
| 2:35 PM | 3:00 PM | Designing Microbes for Sustainability, Pam Silver, Harvard |
| 3:00 PM | 3:25 PM | Mechanistic understanding of microbial interactions for the rational design of food cultures, Ahmad Adel Zeidan, Chr. Hansen |
| 3:25 PM | 3:55 PM | Afternoon Coffee Break |
| 3:55 PM | 4:15 PM | Engineering Anaerobic Fungal-Bacteria Consortia for Medium Chain Fatty Acid Production from Lignocellulosic Biomass, Byung-Chul Kim, University of Toronto |
| 4:15 PM | 4:35 PM | A Rapid Evolutionary Journey Towards Obligate Mutualism, Giovanni Scarinci, Max Planck Institute for Terrestrial Microbiology |
| 4:35 PM | 4:40 PM | Lightning Talk: Escherichia coli Promoters with Consistent Expression throughout the Murine Gut, Jeremy Armetta, Technical University of Denmark |
| 4:40 PM | 4:45 PM | Lightning Talk: Engineering a Targeted Probiotic Yeast Drug Delivery System for Treatment of Inflammatory Bowel Diseases, Mairead Heavey, UNC Chapel Hill |
| 4:45 PM | 4:50 PM | Lightning Talk: Indole-3-Acetate, a Microbiome Derived Tryptophan Metabolite, Provides Protection Against NAFLD and Exhibits Anti-Inflammatory Activity through Adipose-Liver Axis, Karin Yanagi, Tufts University |
| 4:50 PM | 5:50 PM | Poster Session B |
| December 11, 2022 | ||
| 8:00 AM | 4:00 PM | Registration & Check In |
| 8:30 AM | 9:00 AM | Breakfast + Morning Coffee |
| Day 3 | ||
| 9:00 AM | 10:00 AM | Introduction & Keynote |
| 9:00 AM | 9:10 AM | Day 3 Introduction by Chair: Mark Charbonneau, Solarea Bio |
| 9:10 AM | 10:00 AM | KEYNOTE: Resource competition predicts assembly of in vitro gut bacterial communities, KC Huang, Stanford University |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 12:10 PM | Therapeutics (Clinical Applications and Drug Development) Part 2 Chair: Mark Charbonneau |
| 10:30 AM | 10:35 AM | Session Introduction: Mark Charbonneau, Solarea Bio |
| 10:35 AM | 11:00 AM | Genetically Engineered Microbial Medicines, Lauren Popov, Novome Biotechnologies |
| 11:00 AM | 11:25 AM | Jan Peter van Pijkeren, University of Wisconsin Madison |
| 11:25 AM | 11:50 AM | Leveraging Bacterial Secretion Systems to Develop Therapeutic Designer Probiotics, Cammie Lesser, Harvard Medical School |
| 11:50 AM | 12:10 PM | Niche Exclusion of a Lung Pathogen in Mice with Designed Probiotic Communities, Kelsey Hern, University of California Berkeley |
| 12:10 PM | 1:10 PM | Lunch |
| 1:10 PM | 2:25 PM | Learning Engineering Principles from Natural Communities Chair: Greg Medlock |
| 1:10 PM | 1:15 PM | Session Introduction: Greg Medlock, Vedanta Biosciences |
| 1:15 PM | 1:40 PM | Bacterial bile acid metabolites affect host physiology, Sloan Devlin, Harvard University |
| 1:40 PM | 2:05 PM | Engineered Native E. coli Allow Persistent Physiological Change in Conventionally-Raised Hosts, Amir Zarrinpar, UC San Diego |
| 2:05 PM | 2:25 PM | Metabolic Flux Analysis Identifies Unexpected Metabolite Exchanges in E. coli Co-Culture, Yu Jun Hong, University of Michigan |
| 2:25 PM | 2:35 PM | Closing Statements, Megan McClean & Mark Charbonneau |
