Program
Saturday, November 12
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Saturday, November 12
| 8:00 AM - 12:00 PM | Registration |
| 9:00 AM - 9:15 AM | Welcome Remarks |
| 9:15 AM - 11:30 AM | Session 1: Gene and Drug Delivery |
| 9:15 AM - 9:45 AM | Invited Speaker: Directed Evolution of New Viruses for Therapeutic Gene Delivery - David Schaffer, University of California, Berkeley |
| 9:45 AM - 10:00 AM | Discovery of Polymers for Nucleic Acid Delivery Using Combinatorial and Cheminformatics Methods - Kaushal Rege, Arizona State University |
| 10:00 AM - 10:15 AM | Histone-Targeted Gene Delivery Carriers for Bone Regeneration - Erik Munsell, University of Delaware |
| 10:15 AM - 10:45 AM | Break |
| 10:45 AM - 11:00 AM | Probing Cellular-Particle Interactions and Deformability in the Design of Vascular-Targeted Carriers - Lola Eniola-Adefeso, University of Michigan |
| 11:00 AM - 11:15 AM | Design of Polyelectrolyte Multilayers to Promote Immune Tolerance - Christopher Jewell, University of Maryland |
| 11:15 AM - 11:30 AM | Multi-Stage Drug Delivery System for Enhanced Payload Delivery to Lymph Node Cells - Susan N. Thomas, Georgia Institute of Technology |
| 11:30 AM - 1:00 PM | Lunch |
| 1:00 PM - 2:45 PM | Session 2: Immunoengineering |
| 1:00 PM - 1:30 PM | Invited Speaker: Tumor Targeting and Immunotherapy Enabled By an Engineered Peptide-Fc Fusion - Jennifer Cochran - Stanford University |
| 1:30 PM - 1:45 PM | Dendritic Cell-Targeted Immunomodulation for Tolerance - Benjamin Keselowsky, University of Florida |
| 1:45 PM - 2:00 PM | Immunoengineered Particles As Artificial Immune Cells: the Importance of Size and Shape - Jordan Green, Johns Hopkins University |
| 2:00 PM - 2:15 PM | Controlling Immune Cell Dynamics Using Microfluidics - Savas Tay, University of Chicago |
| 2:15 PM - 2:30 PM | Quantitative, Molecular-Level Analysis of the Serum Antibody Repertoire Reveals Unanticipated Features of the Response to Influenza Vaccination - Jiwon Lee, University of Texas at Austin |
| 2:30 PM - 2:45 PM | Synthetic Biology in Cancer Cellular Immunotherapy - Wilson Wong, Boston University |
| 2:45 PM - 3:15 PM | Break |
| 3:15 PM - 5:00 PM | Session 3: Biopharmaceuticals |
| 3:15 PM - 3:45 PM | Invited Speaker: Dane Wittrup |
| 3:45 PM - 4:00 PM | Biopharmaceutical Informatics: A Strategic Vision for Improved Translation of Biologic Drug Discoveries into Drug Products - Sandeep Kumar, Pfizer Inc. |
| 4:00 PM - 4:15 PM | Translatable Affibody Ligand Discovery: Engineered Biopanning, Deep Sequence-Guided Library Design, and Pharmacokinetic Modulation - Benjamin Hackel, University of Minnesota |
| 4:15 PM - 4:30 PM | Engineered Multivalency for Enhanced Efficacy of HER3-Targeted Affibodies - Steven Jay, University of Maryland |
| 4:30 PM - 4:45 PM | Evaluation of Invertebrate Hemoglobins As Novel Blood Substitutes - Jacob Elmer, Villanova University |
| 4:45 PM - 5:00 PM | Engineering Antibody Fabs for Long Acting Delivery to the Eye - Robert Kelley, Genetech Inc. |
| 5:00 PM - 7:00 PM | Poster Session |
Sunday, November 13 |
|
| 8:00 AM - 9:00 AM | Registration |
| 9:00 AM - 9:15 AM | Welcome Introduction |
| 9:15 AM - 11:30 AM | Session 4: Biomanufacturing |
| 9:15 AM - 9:45 AM | Invited Speaker: Discovery and Engineering of Disulfide Bond Switches in Mammals - Chaitan Khosla, Stanford University |
| 9:45 AM - 10:00 AM | Development of a CHO-Based Cell-Free Biomanufacturing Platform for Synthesis of Active Human Monoclonal Antibodies - Rey Martin, Northwestern University |
| 10:00 AM - 10:15 AM | Next-Generation Sequencing and Omics Technologies for Biotherapeutic Manufacturing Development - Joost Groot, Biogen |
| 10:15 AM - 10:45 AM | Break |
| 10:45 AM - 11:00 AM | Stem Cell-Based Product Biomanufacturing: From Cultivation Modalities to Population Based-Models - Emmanuel Tzanakakis, Tufts University |
| 11:00 AM - 11:15 AM | Sugar and Spice: Systems Biotechnology Approaches to Interpret and Improve Mammalian Cell Factories - Michael Betenbaugh, Johns Hopkins University |
| 11:15 AM - 11:30 AM | Recent Developments in Downstream Bioprocessing: Multimodal Chromatography, Affinity Precipitation and Integrated Bioprocessing - Steve Cramer, Rensselaer Polytechnic Institute |
| 11:30 AM - 1:00 PM | Lunch |
| 1:00 PM - 3:00 PM | Session 5: Entrepreneurship |
| 1:00 PM - 2:30 PM | Panel Presentations: Grace Colon (New Science Venture), Mark Davis (California Institute of Technology), Katharine Ku (Stanford University), Krishnendu Roy (Georgia Institute of Technology), Josh Vose (Medtronic Advance Energy) |
| 2:30 PM - 3:00 PM | Discussion |
| 3:00 PM - 3:30 PM | Break |
| 3:30 PM - 5:15 PM | Session 6: Stem Cells |
| 3:30 PM - 4:00 PM | Invited Speaker: Defined, Xeno-Free Platforms for Manufacturing Cardiovascular Cell Types from Human Pluripotent Stem Cells - Sean Palecek, University of Wisconsin, Madison |
| 4:00 PM - 4:15 PM | Engineered Single Human iPSC-Cardiomyocytes to Assay Contractile Defects Induced By Drugs and Disease States - Alexandre Ribeiro, Stanford University |
| 4:15 PM - 4:30 PM | Distinct and Shared Determinants Impacting Cardiomyocyte Contractility in Multi-Lineage Competent Ethnically Diverse iPSCs - Martin Tomov, SUNY Polytechnic Institute |
| 4:30 PM - 4:45 PM | De Novo Prediction of Human Reprogramming Using Nuclear Imaging Data - Krishanu Saha, University of Wisconsin-Madison |
| 4:45 PM - 5:00 PM | Vascular Differentiation and Engineering from Human Pluripotent Stem Cells, Sharon Gerecht, Johns Hopkins University |
| 5:00 PM - 5:15 PM | Utilizing Developmental Cues to ‘Engineer’ Native Tissues from Human Induced Pluripotent Stem Cells (iPSC) - Nidhi Bhutani, Stanford University |
| 5:15 PM - 5:30 PM | Closing Remarks |
